Literature DB >> 15054667

[Fibrin glue for closing conjunctival wounds in ophthalmic surgery].

T Krzizok1.   

Abstract

BACKGROUND: Tissue adhesives offer the attractive prospect of sutureless surgery and provide a mechanism for repairing potentially difficult surgical wounds. We examined the ability of fibrin glue--instead of sutures--to close conjunctival wounds at the end of different ophthalmic surgeries. METHODS AND PATIENTS: Between 2002 and 2003 the fibrin glue Beriplast was used in our department to close the conjunctival wound in 100 eye muscle surgeries, 10 scleral buckling procedures in retinal detachment, and 20 pars plana vitrectomies.
RESULTS: No patient showed postoperative adverse or allergic reactions, bacterial infections, inflammation, or delayed healing. The healing process of the conjunctiva takes a similar time course as in suture closure, but without disturbing suture ends and knots. In children with extensive Tenon's fascia, adaptation of the conjunctiva is safer using sutures. The necessary time using fibrin glue is reduced to one-fourth of the usual 4-8 min necessary for suturing the conjunctiva. The costs for fibrin glue are the same as for Vicryl 9/0, i.e., approximately 18-20 Euros per patient.
CONCLUSIONS: Fibrin glue for closing conjunctival wounds results in good adaptation, is time saving, effective, and not more expensive than a suture with a high-end needle. Especially the thin atrophic conjunctiva in adults will tear using sutures in contrast to the very fast and effective adaptation with fibrin glue. Application of fibrin glue is limited in children with extensive Tenon's fascia: in these patients a suture is superior for good adaptation of the conjunctiva.

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Year:  2004        PMID: 15054667     DOI: 10.1007/s00347-004-1015-3

Source DB:  PubMed          Journal:  Ophthalmologe        ISSN: 0941-293X            Impact factor:   1.059


  12 in total

1.  The use of fibrin glue in mucous membrane grafting of the fornix.

Authors:  M T Watts; R Collin
Journal:  Ophthalmic Surg       Date:  1992-10

2.  [Fibrin gluing of the extraocular eye muscles. Experimental use in the rabbit].

Authors:  M W Aichmair; H Aichmair; F Lintner
Journal:  Klin Monbl Augenheilkd       Date:  1988-11       Impact factor: 0.700

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Authors:  W de Decker
Journal:  Klin Monbl Augenheilkd       Date:  1968       Impact factor: 0.700

Review 4.  Astigmatism after phacoemulsification with posterior chamber lens implantation: small incision technique with fibrin adhesive for wound closure.

Authors:  U Mester; M Zuche; M Rauber
Journal:  J Cataract Refract Surg       Date:  1993-09       Impact factor: 3.351

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Authors:  H Flick
Journal:  Klin Monbl Augenheilkd       Date:  1981-03       Impact factor: 0.700

6.  [Sealing of conjunctival fistulas by means of a fibrinogen adhesive (author's transl)].

Authors:  H W Holtmann
Journal:  Klin Monbl Augenheilkd       Date:  1980-09       Impact factor: 0.700

7.  [Material for and fixation of conjunctival reconstruction. Comparative animal experiment].

Authors:  F Härting; K B Mellin
Journal:  Fortschr Ophthalmol       Date:  1982

8.  [Healing process and complications after eye muscle surgery].

Authors:  K Scharwey; M Gräf; R Becker; H Kaufmann
Journal:  Ophthalmologe       Date:  2000-01       Impact factor: 1.059

9.  [Restoration of a reasonably clear lens after perforating injury].

Authors:  W Buschmann
Journal:  Klin Monbl Augenheilkd       Date:  1982-12       Impact factor: 0.700

10.  [Experimental findings with a fibrin tissue adhesive in conjunctival and skleral surgery in a rabbit model (author's transl)].

Authors:  F Härting; K B Mellin
Journal:  Klin Monbl Augenheilkd       Date:  1981-07       Impact factor: 0.700

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  2 in total

1.  [Classification of biomedical research reports as a reference for evidence-based medicine in ophthalmology. A survey considering as example the journal Der Ophthalmologe].

Authors:  H P N Scholl; M Fleckenstein; T U Krohne; F G Holz
Journal:  Ophthalmologe       Date:  2005-12       Impact factor: 1.059

2.  Comparison of fibrin glue and sutures for conjunctival wound closure in strabismus surgery.

Authors:  Jae Hyung Lee; Nam Yeo Kang
Journal:  Korean J Ophthalmol       Date:  2011-05-24
  2 in total

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