Glial changes in primate cerebral cortex following long-term sensory deprivation.

Significant morphological modifications in the layout of primate-specific (interlaminar) astroglia were found in somatosensory areas 3a, 3b, 1 and 2 eleven to thirteen months after transection of the posterior spinal cord in adult Macaca monkeys. These observations plus lack of evidence of a persistent reactive astrocytosis suggest that changes in the spatial arrangement of interlaminar glia may be an integral part of the long-term process of structural reorganization of the cerebral cortex following cortical deafferentation.