| Literature DB >> 15053600 |
Terry A Goody1, David M J Lilley, David G Norman.
Abstract
We have used a novel electrophoretic approach to determine the chirality of a four-way helical junction in RNA. From our experiments we conclude that the handedness of the helical junction in the complete ribozyme is opposite to that found in the free junction and is therefore constrained by the interaction between the unpaired loops of the ribozyme.Entities:
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Year: 2004 PMID： 15053600 DOI： 10.1021/ja0319240
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419