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Literature DB >> 15053581

Photolithographic synthesis of peptoids.

Shuwei Li¹, Dawn Bowerman, Nishanth Marthandan, Stanley Klyza, Kevin J Luebke, Harold R Garner, Thomas Kodadek.

Abstract

We describe a novel photolithographic approach to the synthesis of peptoids (oligo-N-substituted glycines). This strategy enables the construction of a spatially addressable peptoid microarray, thus providing a potentially powerful tool for the discovery of protein ligands.

Entities: Chemical

Year: 2004 PMID： 15053581 DOI： 10.1021/ja039565w

Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419

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Cited

8 in total

1. Protein "fingerprinting" in complex mixtures with peptoid microarrays.

Authors: M Muralidhar Reddy; Thomas Kodadek
Journal: Proc Natl Acad Sci U S A Date: 2005-08-25 Impact factor: 11.205

2. Protein farnesyltransferase-catalyzed isoprenoid transfer to peptide depends on lipid size and shape, not hydrophobicity.

Authors: Thangaiah Subramanian; Suxia Liu; Jerry M Troutman; Douglas A Andres; H Peter Spielmann
Journal: Chembiochem Date: 2008-11-24 Impact factor: 3.164

Photolithographic synthesis of peptoids.

1. Protein "fingerprinting" in complex mixtures with peptoid microarrays.

2. Protein farnesyltransferase-catalyzed isoprenoid transfer to peptide depends on lipid size and shape, not hydrophobicity.

Review 3. Advances in Development of Antimicrobial Peptidomimetics as Potential Drugs.

4. Small molecule microarrays of RNA-focused peptoids help identify inhibitors of a pathogenic group I intron.

5. Fluorescence quenchers for hydrazone and oxime orthogonal bioconjugation.

6. Cell Penetrating Peptoids (CPPos): Synthesis of a Small Combinatorial Library by Using IRORI MiniKans.

Review 7. Solid-phase synthesis of N-substituted glycine oligomers (alpha-peptoids) and derivatives.

8. Peptoids and polyamines going sweet: Modular synthesis of glycosylated peptoids and polyamines using click chemistry.