Literature DB >> 15053344

Antimutagenic and antiradical properties of flavones from the roots of Scutellaria baicalensis georgi.

Dorota Woźniak1, Eliza Lamer-Zarawska, Adam Matkowski.   

Abstract

The four flavonoids baicalin, baicalein, wogonoside, and wogonin have been isolated from Scutellaria baicalensis (Lamiaceae) root extract as main bioactive components. We evaluated their antimutagenic activity as potential chemopreventive natural substances using the Ames test. Free radical scavenging properties have also been measured with the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. Both crude extract and isolated flavone glycosides and aglycones have antimutagenic and free radical scavenging properties. The lipophilic flavone baicalein has been confirmed to be the most powerful antimutagen among the compounds tested.

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Year:  2004        PMID： 15053344     DOI： 10.1002/food.200200230

Source DB:  PubMed          Journal:  Nahrung        ISSN： 0027-769X


  9 in total

1.  Two types of O-methyltransferase are involved in biosynthesis of anticancer methoxylated 4'-deoxyflavones in Scutellaria baicalensis Georgi.

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Journal:  Plant Biotechnol J       Date:  2021-09-14       Impact factor: 13.263

2.  Optimization of the extraction of total flavonoids from Scutellaria baicalensis Georgi using the response surface methodology.

Authors:  Yanqing Liu; Hongwu Wang; Xuan Cai
Journal:  J Food Sci Technol       Date:  2014-03-01       Impact factor: 2.701

3.  H2O2 Improves Quality of Radix scutellariae Through Anti-oxidant Effect.

Authors:  Song Qi; Cao Wu-Lin; Jiang Hua; Zhang Ai-Hua; Meng Xiang-Cai
Journal:  Pharmacogn Mag       Date:  2016 Jan-Mar       Impact factor: 1.085

4.  Scutellaria baicalensis, the golden herb from the garden of Chinese medicinal plants.

Authors:  Qing Zhao; Xiao-Ya Chen; Cathie Martin
Journal:  Sci Bull (Beijing)       Date:  2016-07-08       Impact factor: 11.780

5.  Influence of Culture Medium Composition and Light Conditions on the Accumulation of Bioactive Compounds in Shoot Cultures of Scutellaria lateriflora L. (American Skullcap) Grown In Vitro.

Authors:  Beata Kawka; Inga Kwiecień; Halina Ekiert
Journal:  Appl Biochem Biotechnol       Date:  2017-06-01       Impact factor: 2.926

6.  Baicalin Ameliorates Experimental Liver Cholestasis in Mice by Modulation of Oxidative Stress, Inflammation, and NRF2 Transcription Factor.

Authors:  Kezhen Shen; Xiaowen Feng; Hao Pan; Feng Zhang; Haiyang Xie; Shusen Zheng
Journal:  Oxid Med Cell Longev       Date:  2017-07-05       Impact factor: 6.543

7.  Adsorption and Purification of Baicalin from Scutellaria baicalensis Georgi Extract by Ionic Liquids (ILs) Grafted Silica.

Authors:  Yunchang Fan; Di Wu; Sheli Zhang
Journal:  Molecules       Date:  2021-04-16       Impact factor: 4.411

8.  Antimutagenic activity and radical scavenging activity of water infusions and phenolics from ligustrum plants leaves.

Authors:  Milan Nagy; Lívia Krizková; Pavel Mucaji; Zuzana Kontseková; Frantisek Sersen; Juraj Krajcovic
Journal:  Molecules       Date:  2009-01-22       Impact factor: 4.411

Review 9.  Anticancer Plants: A Review of the Active Phytochemicals, Applications in Animal Models, and Regulatory Aspects.

Authors:  Tariq Khan; Muhammad Ali; Ajmal Khan; Parveen Nisar; Sohail Ahmad Jan; Shakeeb Afridi; Zabta Khan Shinwari
Journal:  Biomolecules       Date:  2019-12-27
  9 in total

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