Literature DB >> 15051628

Hydrogen sulphide: an endogenous stimulant of capsaicin-sensitive primary afferent neurons?

L A Chahl1.   

Abstract

Hydrogen sulphide (H(2)S) is a gas best known for its rotten egg smell. The toxic effects of high concentrations of H(2)S have been extensively investigated. It is known that H(2)S is generated in mammalian systems, but little is known of its effects in physiological concentrations. In the present issue of this journal, Patacchini et al. present evidence that H(2)S stimulates capsaicin-sensitive primary afferent neurons to release tachykinins in the rat urinary bladder. The possible significance of this finding is discussed in this commentary.

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Year:  2004        PMID： 15051628      PMCID： PMC1574936          DOI： 10.1038/sj.bjp.0705765

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  9 in total

1.  The capsaicin receptor: a heat-activated ion channel in the pain pathway.

Authors:  M J Caterina; M A Schumacher; M Tominaga; T A Rosen; J D Levine; D Julius
Journal:  Nature       Date:  1997-10-23       Impact factor: 49.962

2.  Two's company, three's a crowd: can H2S be the third endogenous gaseous transmitter?

Authors:  Rui Wang
Journal:  FASEB J       Date:  2002-11       Impact factor: 5.191

3.  The vasorelaxant effect of H(2)S as a novel endogenous gaseous K(ATP) channel opener.

Authors:  W Zhao; J Zhang; Y Lu; R Wang
Journal:  EMBO J       Date:  2001-11-01       Impact factor: 11.598

4.  Hydrogen sulfide is produced in response to neuronal excitation.

Authors:  Ko Eto; Miki Ogasawara; Ken Umemura; Yasuo Nagai; Hideo Kimura
Journal:  J Neurosci       Date:  2002-05-01       Impact factor: 6.167

Review 5.  Toxicology of hydrogen sulfide.

Authors:  R J Reiffenstein; W C Hulbert; S H Roth
Journal:  Annu Rev Pharmacol Toxicol       Date:  1992       Impact factor: 13.820

6.  The smooth muscle relaxant effect of hydrogen sulphide in vitro: evidence for a physiological role to control intestinal contractility.

Authors:  B Teague; S Asiedu; P K Moore
Journal:  Br J Pharmacol       Date:  2002-09       Impact factor: 8.739

Review 7.  Tachykinins and calcitonin gene-related peptide (CGRP) as co-transmitters released from peripheral endings of sensory nerves.

Authors:  C A Maggi
Journal:  Prog Neurobiol       Date:  1995-01       Impact factor: 11.685

8.  The possible role of hydrogen sulfide as an endogenous neuromodulator.

Authors:  K Abe; H Kimura
Journal:  J Neurosci       Date:  1996-02-01       Impact factor: 6.167

Review 9.  Novel neural modulators.

Authors:  Darren Boehning; Solomon H Snyder
Journal:  Annu Rev Neurosci       Date:  2003       Impact factor: 12.449
  9 in total
  2 in total

Review 1.  Parallel evolution of nitric oxide signaling: diversity of synthesis and memory pathways.

Authors:  Leonid L Moroz; Andrea B Kohn
Journal:  Front Biosci (Landmark Ed)       Date:  2011-06-01

2.  Inhibition of ROS-activated p38MAPK pathway is involved in the protective effect of H2S against chemical hypoxia-induced inflammation in PC12 cells.

Authors:  Aiping Lan; Wenming Xu; Hui Zhang; Xiaoxiao Hua; Dongdan Zheng; Runmin Guo; Ning Shen; Fen Hu; Jianqiang Feng; Donghong Liu
Journal:  Neurochem Res       Date:  2013-04-27       Impact factor: 3.996
  2 in total

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