Arthur C K Cheng1, Ricky W K Law, Alvin L Young, Dennis S C Lam. 1. Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong, 3F, Hong Kong Eye Hospital, 147K Argyle Street, Kowloon, Hong Kong, China. arthurcheng@cuhk.edu.hk
Abstract
OBJECTIVE: To report the confocal microscopic findings of 2 different cases of steroid-induced glaucoma after LASIK. DESIGN: Observational case report of 2 cases. METHODS: Two cases of steroid-induced glaucoma after LASIK were selected. Examination with a white-light tandem slit-scanning confocal microscope was performed in addition to routine slit-lamp biomicroscopy. MAIN OUTCOME MEASURES: In vivo confocal findings at the flap interface. RESULTS: In both cases, the interfaces were identified at a deeper level than expected. Confocal microscopic examination did not show mononuclear cells and granulocytes typically seen in patients with classic diffuse lamellar keratitis. CONCLUSION: Our findings confirm that steroid-induced glaucoma after LASIK is not associated with the collection of inflammatory cells. The treatment option of lowering the intraocular pressure is effective in treating the disease, even without anti-inflammatory medications. Confocal in vivo microscopy is a useful tool to study the course of steroid-induced glaucoma after LASIK in humans.
OBJECTIVE: To report the confocal microscopic findings of 2 different cases of steroid-induced glaucoma after LASIK. DESIGN: Observational case report of 2 cases. METHODS: Two cases of steroid-induced glaucoma after LASIK were selected. Examination with a white-light tandem slit-scanning confocal microscope was performed in addition to routine slit-lamp biomicroscopy. MAIN OUTCOME MEASURES: In vivo confocal findings at the flap interface. RESULTS: In both cases, the interfaces were identified at a deeper level than expected. Confocal microscopic examination did not show mononuclear cells and granulocytes typically seen in patients with classic diffuse lamellar keratitis. CONCLUSION: Our findings confirm that steroid-induced glaucoma after LASIK is not associated with the collection of inflammatory cells. The treatment option of lowering the intraocular pressure is effective in treating the disease, even without anti-inflammatory medications. Confocal in vivo microscopy is a useful tool to study the course of steroid-induced glaucoma after LASIK in humans.