Literature DB >> 15051064

Biscoumarin: new class of urease inhibitors; economical synthesis and activity.

Khalid Mohammed Khan1, Sajid Iqbal, Muhammad Arif Lodhi, Ghulam Murtaza Maharvi, Zia Ullah, Muhammad Iqbal Choudhary, Atta-Ur Rahman, Shahnaz Perveen.   

Abstract

A variety of biscoumarins (1-21) with variable substituents at C-11 were synthesized with an improved method and evaluated as urease inhibitors. The synthesized compounds showed varying degree of urease inhibitory activity ranging from 15.06-91.35 microM. The size and electron donating or withdrawing effects of substituents influenced the activity, which lead to the urease inhibitors.

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Year:  2004        PMID： 15051064     DOI： 10.1016/j.bmc.2004.01.010

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN： 0968-0896            Impact factor:   3.641


  9 in total

Review 1.  The molecular diversity scope of 4-hydroxycoumarin in the synthesis of heterocyclic compounds via multicomponent reactions.

Authors:  Ghodsi Mohammadi Ziarani; Razieh Moradi; Tahereh Ahmadi; Parisa Gholamzadeh
Journal:  Mol Divers       Date:  2019-01-29       Impact factor: 2.943

Review 2.  A review on convenient synthesis of substituted coumarins using reuseable solid acid catalysts.

Authors:  Susheel Gulati; Rajvir Singh; Suman Sangwan
Journal:  RSC Adv       Date:  2021-09-01       Impact factor: 4.036

3.  Structural basis of binding and rationale for the potent urease inhibitory activity of biscoumarins.

Authors:  Muhammad Arif Lodhi; Sulaiman Shams; Muhammad Iqbal Choudhary; Atif Lodhi; Zaheer Ul-Haq; Saima Jalil; Sarfraz Ahmad Nawaz; Khalid Mohammed Khan; Sajid Iqbal; Atta-ur Rahman
Journal:  Biomed Res Int       Date:  2014-09-09       Impact factor: 3.411

4.  Sulfonamide-Linked Ciprofloxacin, Sulfadiazine and Amantadine Derivatives as a Novel Class of Inhibitors of Jack Bean Urease; Synthesis, Kinetic Mechanism and Molecular Docking.

Authors:  Pervaiz Ali Channar; Aamer Saeed; Fernando Albericio; Fayaz Ali Larik; Qamar Abbas; Mubashir Hassan; Hussain Raza; Sung-Yum Seo
Journal:  Molecules       Date:  2017-08-16       Impact factor: 4.411

5.  An Efficient and Versatile Deep Eutectic Solvent-Mediated Green Method for the Synthesis of Functionalized Coumarins.

Authors:  Ishfaq Ahmad Rather; Rashid Ali
Journal:  ACS Omega       Date:  2022-03-15

6.  Sulfonyl-bridged (copper-immobilized nickel ferrite) with activated montmorillonite, [(NiFe2O4@Cu)SO2(MMT)]: a new class of magnetically separable clay nanocomposite systems towards Hantzsch synthesis of coumarin-based 1,4-dihydropyridines.

Authors:  Behzad Zeynizadeh; Soleiman Rahmani
Journal:  RSC Adv       Date:  2019-03-11       Impact factor: 3.361

7.  Meglumine-Promoted Eco-Compatible Pseudo-Three-Component Reaction for the Synthesis of 1,1-Dihomoarylmethane Scaffolds and Their Green Credentials.

Authors:  Manan S Patel; Jaydeepkumar N Parekh; Dipakkumar D Chudasama; Harsh C Patel; Priyanka Dalwadi; Anju Kunjadiya; Vaibhav Bhatt; Kesur R Ram
Journal:  ACS Omega       Date:  2022-08-18

8.  Analysis of 1-Aroyl-3-[3-chloro-2-methylphenyl] Thiourea Hybrids as Potent Urease Inhibitors: Synthesis, Biochemical Evaluation and Computational Approach.

Authors:  Samina Rasheed; Mubashir Aziz; Aamer Saeed; Syeda Abida Ejaz; Pervaiz Ali Channar; Seema Zargar; Qamar Abbas; Humidah Alanazi; Mumtaz Hussain; Mona Alharbi; Song Ja Kim; Tanveer A Wani; Hussain Raza
Journal:  Int J Mol Sci       Date:  2022-10-01       Impact factor: 6.208

9.  Efficient Catalyst One-Pot Synthesis of 7-(Aryl)-10,10-dimethyl-10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H)-dione Derivatives Complemented by Antibacterial Activity.

Authors:  Yasameen K Al-Majedy; Ahmed A Al-Amiery; Abdul Amir H Kadhum; Abu Bakar Mohamad
Journal:  Biomed Res Int       Date:  2016-07-31       Impact factor: 3.411
  9 in total

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