Literature DB >> 15050909

The new kid on the block(ade) of the IGF-1 receptor.

Derek LeRoith1, Lee Helman.   

Abstract

The insulin-like growth factors (IGF) system, and particularly the IGF-1 receptor, has recently become the subject of major interest in the arena of cancer research. Its involvement in cancer cell growth and survival makes the system an excellent target as potential adjunct therapy to standard chemotherapy.

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Year:  2004        PMID： 15050909     DOI： 10.1016/s1535-6108(04)00054-6

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  24 in total

1.  Klotho is silenced through promoter hypermethylation in gastric cancer.

Authors:  Liangjing Wang; Xian Wang; Xiaojia Wang; Pan Jie; Haiqi Lu; Shengjie Zhang; Xiaoying Lin; Emily Ky Lam; Yan Cui; Jun Yu; Hongchuan Jin
Journal:  Am J Cancer Res       Date:  2010-11-10       Impact factor: 6.166

2.  Synthesis of aryl-heteroaryl ureas (AHUs) based on 4-aminoquinoline and their evaluation against the insulin-like growth factor receptor (IGF-1R).

Authors:  William Engen; Terrence E O'Brien; Brendan Kelly; Jacinda Do; Liezel Rillera; Lance K Stapleton; Jack F Youngren; Marc O Anderson
Journal:  Bioorg Med Chem       Date:  2010-06-25       Impact factor: 3.641

3.  Sequence-specific targeting of IGF-I and IGF-IR genes by camptothecins.

Authors:  Kahina Oussedik; Jean-Christophe François; Ludovic Halby; Catherine Senamaud-Beaufort; Géraldine Toutirais; Sabrina Dallavalle; Yves Pommier; Claudio Pisano; Paola B Arimondo
Journal:  FASEB J       Date:  2010-02-23       Impact factor: 5.191

Review 4.  Inhibitors of insulin-like growth factor signaling: a therapeutic approach for breast cancer.

Authors:  Deepali Sachdev; Douglas Yee
Journal:  J Mammary Gland Biol Neoplasia       Date:  2006-01       Impact factor: 2.673

Review 5.  Cardiac myocyte cell cycle control in development, disease, and regeneration.

Authors:  Preeti Ahuja; Patima Sdek; W Robb MacLellan
Journal:  Physiol Rev       Date:  2007-04       Impact factor: 37.312

6.  Down-regulation of IGF-1R expression inhibits growth and enhances chemosensitivity of endometrial carcinoma in vitro.

Authors:  Shanrong Shu; Yuebo Yang; Xiaomao Li; Tian Li; Yu Zhang; Chengfang Xu; Changyan Liang; Xiaoyun Wang
Journal:  Mol Cell Biochem       Date:  2011-03-26       Impact factor: 3.396

7.  MicroRNA-497 regulates cell proliferation in hepatocellular carcinoma.

Authors:  Wen-Zhou Ding; Qing-Feng Ni; Ye-Ting Lu; Liang-Liang Kong; Jian-Jun Yu; Long-Wei Tan; Lian-Bao Kong
Journal:  Oncol Lett       Date:  2015-12-01       Impact factor: 2.967

8.  Addiction to elevated insulin-like growth factor I receptor and initial modulation of the AKT pathway define the responsiveness of rhabdomyosarcoma to the targeting antibody.

Authors:  Liang Cao; Yunkai Yu; Isaac Darko; Duane Currier; Linnia H Mayeenuddin; Xiaolin Wan; Chand Khanna; Lee J Helman
Journal:  Cancer Res       Date:  2008-10-01       Impact factor: 12.701

Review 9.  Inhibition of the insulin-like growth factor-1 receptor (IGF1R) tyrosine kinase as a novel cancer therapy approach.

Authors:  Rongshi Li; Alan Pourpak; Stephan W Morris
Journal:  J Med Chem       Date:  2009-08-27       Impact factor: 7.446

10.  Insulin growth factor signaling is regulated by microRNA-486, an underexpressed microRNA in lung cancer.

Authors:  Yong Peng; Yuntao Dai; Charles Hitchcock; Xiaojuan Yang; Edmund S Kassis; Lunxu Liu; Zhenghua Luo; Hui-Lung Sun; Ri Cui; Huijun Wei; Taewan Kim; Tae Jin Lee; Young-Jun Jeon; Gerard J Nuovo; Stefano Volinia; Qianchuan He; Jianhua Yu; Patrick Nana-Sinkam; Carlo M Croce
Journal:  Proc Natl Acad Sci U S A       Date:  2013-08-26       Impact factor: 11.205
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