Photo-acoustic stimulation increases the amount of 70 kDa heat shock protein (Hsp70) in human whole saliva. A pilot study.

Long-term photo-acoustic stimulation leads to changes in the composition of saliva, which may have a key contribution to the effectivity of this technique in easing mucosal symptoms of psychosomatic patients. In the present study a significant (P <or= 0.01) increase in salivary 70 kDa heat shock protein, Hsp70 was demonstrated in human whole saliva after repeated photo-acoustic stimulation. Increased salivary chaperones may contribute to the effectivity of photo-acoustic stimulation, because of their cytoprotective extracellular actions.