| Literature DB >> 15049650 |
Siham El Fangour1, Alexandre Guy, Valérie Despres, Jean-Pierre Vidal, Jean-Claude Rossi, Thierry Durand.
Abstract
Syntheses of the eight enantiomerically pure diastereomers of the syn-anti-syn phytoprostanes F(1) types I and II are described starting from D- and L-glucose. Key steps include Wittig coupling, Horner Wadsworth Emmons (HWE) reactions, and enantioselective reduction of alpha,beta-unsaturated ketones.Entities:
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Year: 2004 PMID: 15049650 DOI: 10.1021/jo035638i
Source DB: PubMed Journal: J Org Chem ISSN: 0022-3263 Impact factor: 4.354