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Literature DB >> 15046715

A touching picture of nicotinic binding.

Abstract

The snail acetylcholine binding protein (AChBP) is homologous to the extracellular domains of the nicotinic ACh receptors. In this issue of Neuron, Celie et al. show how the crystal structures of AChBP in complexes with carbamylcholine and nicotine reveal the basis for agonist recognition by ACh receptors.

Entities: Chemical

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Year: 2004 PMID： 15046715 DOI： 10.1016/s0896-6273(04)00151-5

Source DB: PubMed Journal: Neuron ISSN： 0896-6273 Impact factor: 17.173

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Cited

9 in total

1. Non-competitive inhibitory activities of morphinan and morphine derivatives at the alpha 3 beta 4 Neuronal nicotinic acetylcholine receptor determined using nonlinear chromatography and chemometric techniques.

Authors: Krzysztof Jozwiak; Ruin Moaddel; Rika Yamaguchi; Alexandre Maciuk; Irving W Wainer
Journal: Pharm Res Date: 2006-08-09 Impact factor: 4.200

2. First-principles calculation of pKa for cocaine, nicotine, neurotransmitters, and anilines in aqueous solution.

Authors: Haiting Lu; Xi Chen; Chang-Guo Zhan
Journal: J Phys Chem B Date: 2007-08-11 Impact factor: 2.991

3. Modeling multiple species of nicotine and deschloroepibatidine interacting with alpha4beta2 nicotinic acetylcholine receptor: from microscopic binding to phenomenological binding affinity.

Authors: Xiaoqin Huang; Fang Zheng; Peter A Crooks; Linda P Dwoskin; Chang-Guo Zhan
Journal: J Am Chem Soc Date: 2005-10-19 Impact factor: 15.419

A touching picture of nicotinic binding.

1. Non-competitive inhibitory activities of morphinan and morphine derivatives at the alpha 3 beta 4 Neuronal nicotinic acetylcholine receptor determined using nonlinear chromatography and chemometric techniques.

2. First-principles calculation of pKa for cocaine, nicotine, neurotransmitters, and anilines in aqueous solution.

3. Modeling multiple species of nicotine and deschloroepibatidine interacting with alpha4beta2 nicotinic acetylcholine receptor: from microscopic binding to phenomenological binding affinity.

Review 4. In pursuit of the high-resolution structure of nicotinic acetylcholine receptors.

5. First-Principles Determination of Molecular Conformations of Indolizidine (-)-235B' in Solution.

Review 6. Targeting brain α7 nicotinic acetylcholine receptors in Alzheimer's disease: rationale and current status.

7. Overexpression and functional characterization of the extracellular domain of the human alpha1 glycine receptor.

Review 8. Structural answers and persistent questions about how nicotinic receptors work.

Review 9. Venom-Derived Neurotoxins Targeting Nicotinic Acetylcholine Receptors.