Literature DB >> 1504344

Fragmentation studies of peptides: the formation of y ions.

P T Kenny1, K Nomoto, R Orlando.   

Abstract

The mechanism for the formation of y ions in the collision-induced dissociation (CID) spectra of protonated peptides produced by fast-atom bombardment was investigated by tandem mass spectrometry and deuterium labelling studies. The results show that a hydrogen atom attached to nitrogen and not to carbon migrates during cleavage of the amide bond. A mechanism based on these results is presented.

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Year:  1992        PMID： 1504344     DOI： 10.1002/rcm.1290060205

Source DB:  PubMed          Journal:  Rapid Commun Mass Spectrom        ISSN： 0951-4198            Impact factor:   2.419


  19 in total

1.  Direct dynamics study of N-protonated diglycine surface-induced dissociation. Influence of collision energy.

Authors:  Yanfei Wang; William L Hase; Kihyung Song
Journal:  J Am Soc Mass Spectrom       Date:  2003-12       Impact factor: 3.109

2.  The mobile proton hypothesis in fragmentation of protonated peptides: a perspective.

Authors:  Robert Boyd; Arpád Somogyi
Journal:  J Am Soc Mass Spectrom       Date:  2010-04-29       Impact factor: 3.109

3.  Tandem mass spectrometric characterization of thiol peptides modified by the chemoselective cationic sulfhydryl reagent (4-iodobutyl)triphenylphosphonium--effects of a cationic thiol derivatization on peptide fragmentation.

Authors:  Jing Wang; Jie Zhang; Brian Arbogast; Claudia S Maier
Journal:  J Am Soc Mass Spectrom       Date:  2011-07-26       Impact factor: 3.109

4.  Primary and secondary locations of charge sites in angiotensin II (M + 2H)2+ ions formed by electrospray ionization.

Authors:  M C Sullards; J A Reiter
Journal:  J Am Soc Mass Spectrom       Date:  2000-01       Impact factor: 3.109

5.  Formation of (bn-1 + H2O) ions by collisional activation of MALDI-formed peptide [M + H]+ ions in a QqTOF mass spectrometer.

Authors:  Yi-Min She; Oleg Krokhin; Victor Spicer; Alexandre Loboda; Gideon Garland; Werner Ens; Kenneth G Standing; John B Westmore
Journal:  J Am Soc Mass Spectrom       Date:  2007-04-05       Impact factor: 3.109

6.  An investigation of the energetics of peptide ion dissociation by laser desorption chemical ionization fourier transform mass spectrometry.

Authors:  J P Speir; I J Amster
Journal:  J Am Soc Mass Spectrom       Date:  1995-11       Impact factor: 3.109

7.  The effect of charge state and the localization of charge on the collision-induced dissociation of peptide ions.

Authors:  K M Downard; K Biemann
Journal:  J Am Soc Mass Spectrom       Date:  1994-11       Impact factor: 3.109

8.  The effect of protonation site on bond strengths in simple peptides: Application of Ab initio and modified neglect of differential overlap bond orders and modified neglect of differential overlap energy partitioning.

Authors:  A Somogyi; V H Wysocki; I Mayer
Journal:  J Am Soc Mass Spectrom       Date:  1994-08       Impact factor: 3.109

9.  The importance of charge-separation reactions in tandem mass spectrometry of doubly protonated angiotensin II formed by electrospray ionization: Experimental considerations and structural implications.

Authors:  J Adams; F H Strobel; A Reiter; M C Sullards
Journal:  J Am Soc Mass Spectrom       Date:  1996-01       Impact factor: 3.109

10.  On the collision-activated fragmentation of proferrioxamines: Evidence for a succinimide-mediated mechanism.

Authors:  G J Feistner; L L Hsieh
Journal:  J Am Soc Mass Spectrom       Date:  1995-09       Impact factor: 3.109
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