| Literature DB >> 15043433 |
Fernando Reyes1, Rocío Martín, Ana Rueda, Rogelio Fernández, David Montalvo, Cristina Gómez, José M Sánchez-Puelles.
Abstract
Two cytotoxic alkaloids, discorhabdins L (1) and I (2), were isolated from Latrunculia brevis and their structures assigned on the basis of detailed spectroscopic analysis and comparison with the known metabolites discorhabdins R (5), D (6), and B (4). Compounds 1 and 2 showed strong in vitro cytotoxicity against a panel of 14 tumor cell lines.Entities:
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Year: 2004 PMID: 15043433 DOI: 10.1021/np0303761
Source DB: PubMed Journal: J Nat Prod ISSN: 0163-3864 Impact factor: 4.050