Literature DB >> 15043433

Discorhabdins I and L, cytotoxic alkaloids from the sponge Latrunculia brevis.

Fernando Reyes1, Rocío Martín, Ana Rueda, Rogelio Fernández, David Montalvo, Cristina Gómez, José M Sánchez-Puelles.   

Abstract

Two cytotoxic alkaloids, discorhabdins L (1) and I (2), were isolated from Latrunculia brevis and their structures assigned on the basis of detailed spectroscopic analysis and comparison with the known metabolites discorhabdins R (5), D (6), and B (4). Compounds 1 and 2 showed strong in vitro cytotoxicity against a panel of 14 tumor cell lines.

Entities:  

Mesh:

Substances:

Year:  2004        PMID: 15043433     DOI: 10.1021/np0303761

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  9 in total

1.  Anti-infective discorhabdins from a deep-water alaskan sponge of the genus Latrunculia.

Authors:  Minkyun Na; Yuanqing Ding; Bin Wang; Babu L Tekwani; Raymond F Schinazi; Scott Franzblau; Michelle Kelly; Robert Stone; Xing-Cong Li; Daneel Ferreira; Mark T Hamann
Journal:  J Nat Prod       Date:  2010-03-26       Impact factor: 4.050

Review 2.  Synthesis of the marine pyrroloiminoquinone alkaloids, discorhabdins.

Authors:  Yasufumi Wada; Hiromichi Fujioka; Yasuyuki Kita
Journal:  Mar Drugs       Date:  2010-04-21       Impact factor: 5.118

3.  Inhibition of nitric oxide (NO) production in lipopolysaccharide (LPS)-activated murine macrophage RAW 264.7 cells by the norsesterterpene peroxide, epimuqubilin A.

Authors:  Sarot Cheenpracha; Eun-Jung Park; Bahman Rostama; John M Pezzuto; Leng Chee Chang
Journal:  Mar Drugs       Date:  2010-03-01       Impact factor: 5.118

4.  New Discorhabdin B Dimers with Anticancer Activity from the Antarctic Deep-Sea Sponge Latrunculia biformis.

Authors:  Fengjie Li; Dorte Janussen; Deniz Tasdemir
Journal:  Mar Drugs       Date:  2020-02-11       Impact factor: 5.118

Review 5.  Chemistry, Chemotaxonomy and Biological Activity of the Latrunculid Sponges (Order Poecilosclerida, Family Latrunculiidae).

Authors:  Fengjie Li; Michelle Kelly; Deniz Tasdemir
Journal:  Mar Drugs       Date:  2021-01-09       Impact factor: 5.118

Review 6.  Cytotoxic Alkaloids Derived from Marine Sponges: A Comprehensive Review.

Authors:  Ahmed M Elissawy; Ebrahim Soleiman Dehkordi; Negin Mehdinezhad; Mohamed L Ashour; Pardis Mohammadi Pour
Journal:  Biomolecules       Date:  2021-02-10

Review 7.  Marine Indole Alkaloids.

Authors:  Natalie Netz; Till Opatz
Journal:  Mar Drugs       Date:  2015-08-06       Impact factor: 5.118

8.  Molecular genomic features associated with in vitro response of the NCI-60 cancer cell line panel to natural products.

Authors:  Julia Krushkal; Simarjeet Negi; Laura M Yee; Jason R Evans; Tanja Grkovic; Alida Palmisano; Jianwen Fang; Hari Sankaran; Lisa M McShane; Yingdong Zhao; Barry R O'Keefe
Journal:  Mol Oncol       Date:  2020-11-24       Impact factor: 7.449

Review 9.  Marine Organisms as Alkaloid Biosynthesizers of Potential Anti-Alzheimer Agents.

Authors:  Elisabete Lima; Jorge Medeiros
Journal:  Mar Drugs       Date:  2022-01-15       Impact factor: 5.118

  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.