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Literature DB >> 15043422

Resveratrol derivatives and their role as potassium channels modulators.

F Orsini¹, L Verotta, M Lecchi, R Restano, G Curia, E Redaelli, E Wanke.

Abstract

A series of stilbenoid analogues of resveratrol (trans-3,4',5-trihydroxystilbene) with a stilbenic or a bibenzylic skeleton have been prepared by partial synthesis from resveratrol and dihydroresveratrol. The synthesized compounds have been evaluated for their ability to modulate voltage-gated channels.

Entities: Chemical

Mesh：

Substances：

Year: 2004 PMID： 15043422 DOI： 10.1021/np0303153

Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050

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Cited

6 in total

1. Inhibition of the activity of human lymphocyte Kv1.3 potassium channels by resveratrol.

Authors: Andrzej Teisseyre; Krystyna Michalak
Journal: J Membr Biol Date: 2007-06-05 Impact factor: 1.843

2. Inhibition of cardiac voltage-gated sodium channels by grape polyphenols.

Authors: C H R Wallace; I Baczkó; L Jones; M Fercho; P E Light
Journal: Br J Pharmacol Date: 2006-10-03 Impact factor: 8.739

3. Semisynthesis and biological evaluation of prenylated resveratrol derivatives as multi-targeted agents for Alzheimer's disease.

Authors: Thanchanok Puksasook; Shinya Kimura; Sarin Tadtong; Jutamas Jiaranaikulwanitch; Jaturong Pratuangdejkul; Worawan Kitphati; Khanit Suwanborirux; Naoki Saito; Veena Nukoolkarn
Journal: J Nat Med Date: 2017-06-09 Impact factor: 2.343

Resveratrol derivatives and their role as potassium channels modulators.

1. Inhibition of the activity of human lymphocyte Kv1.3 potassium channels by resveratrol.

2. Inhibition of cardiac voltage-gated sodium channels by grape polyphenols.

3. Semisynthesis and biological evaluation of prenylated resveratrol derivatives as multi-targeted agents for Alzheimer's disease.

Review 4. Chemically Tuning Resveratrol for the Effective Killing of Gram-Positive Pathogens.

5. Cell Cycle Regulation by Ca²⁺-Activated K⁺ (BK) Channels Modulators in SH-SY5Y Neuroblastoma Cells.

6. Identification and characterization of process-related impurities of trans-resveratrol.

Resveratrol derivatives and their role as potassium channels modulators.

1. Inhibition of the activity of human lymphocyte Kv1.3 potassium channels by resveratrol.

2. Inhibition of cardiac voltage-gated sodium channels by grape polyphenols.

3. Semisynthesis and biological evaluation of prenylated resveratrol derivatives as multi-targeted agents for Alzheimer's disease.

Review 4. Chemically Tuning Resveratrol for the Effective Killing of Gram-Positive Pathogens.

5. Cell Cycle Regulation by Ca2+-Activated K⁺ (BK) Channels Modulators in SH-SY5Y Neuroblastoma Cells.

6. Identification and characterization of process-related impurities of trans-resveratrol.

5. Cell Cycle Regulation by Ca²⁺-Activated K⁺ (BK) Channels Modulators in SH-SY5Y Neuroblastoma Cells.