Literature DB >> 15040584

Role of the cytoskeleton during leukocyte responses.

Miguel Vicente-Manzanares1, Francisco Sánchez-Madrid.   

Abstract

The cytoskeleton is a cellular network of structural, adaptor and signalling molecules that regulates most cellular functions that are related to the immune response, including migration, extravasation, antien recognition, activation and phagocytosis by different subsets of leukocytes. Recently, a large number of regulatory elements and structural constituents of the leukocyte cytoskeleton have been identified. In this review, we discuss the composition and regulation of the different cytoskeletal elements and their role in immune responses.

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Year:  2004        PMID： 15040584     DOI： 10.1038/nri1268

Source DB:  PubMed          Journal:  Nat Rev Immunol        ISSN： 1474-1733            Impact factor:   53.106


  117 in total

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