Literature DB >> 15039364

Helicobacter pylori-mediated gastritis induces local downregulation of secretory leukocyte protease inhibitor in the antrum.

Thomas Wex1, Gerhard Treiber, Manfred Nilius, Michael Vieth, Albert Roessner, Peter Malfertheiner.   

Abstract

Helicobacter pylori-infected subjects exhibited a strong decline in antral secretory leukocyte protease inhibitor (SLPI) levels compared to H. pylori-negative subjects and subjects from whom H. pylori had been eradicated (P = 0.002). This reduction was specific for the antrum, whereas SLPI expression in corpus and duodenum was not affected. Antral SLPI levels were inversely correlated with inflammatory scores of antrum-predominant gastritis.

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Year:  2004        PMID： 15039364      PMCID： PMC375164          DOI： 10.1128/IAI.72.4.2383-2385.2004

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  19 in total

1.  Constitutive and regulated secretion of secretory leukocyte proteinase inhibitor by human intestinal epithelial cells.

Authors:  M Si-Tahar; D Merlin; S Sitaraman; J L Madara
Journal:  Gastroenterology       Date:  2000-06       Impact factor: 22.682

2.  A two-step method for the extraction of high-quality RNA from endoscopic biopsies.

Authors:  Thomas Wex; Gerhard Treiber; Uwe Lendeckel; Peter Malfertheiner
Journal:  Clin Chem Lab Med       Date:  2003-08       Impact factor: 3.694

3.  Secretory leukocyte protease inhibitor interferes with uptake of lipopolysaccharide by macrophages.

Authors:  A Ding; N Thieblemont; J Zhu; F Jin; J Zhang; S Wright
Journal:  Infect Immun       Date:  1999-09       Impact factor: 3.441

Review 4.  Chronic gastritis and Helicobacter pylori.

Authors:  D R Cave
Journal:  Semin Gastrointest Dis       Date:  2001-07

Review 5.  Host cell signaling in Helicobacter pylori infection.

Authors:  M Naumann
Journal:  Int J Med Microbiol       Date:  2001-09       Impact factor: 3.473

6.  Secretory leukocyte protease inhibitor mediates non-redundant functions necessary for normal wound healing.

Authors:  G S Ashcroft; K Lei; W Jin; G Longenecker; A B Kulkarni; T Greenwell-Wild; H Hale-Donze; G McGrady; X Y Song; S M Wahl
Journal:  Nat Med       Date:  2000-10       Impact factor: 53.440

Review 7.  Helicobacter pylori associated gastric pathology.

Authors:  P C Konturek; W Bielański; S J Konturek; E G Hahn
Journal:  J Physiol Pharmacol       Date:  1999-12       Impact factor: 3.011

8.  Induction of chemokine and cytokine responses by Helicobacter pylori in human stomach explants.

Authors:  C Lindholm; M Quiding-Järbrink; H Lönroth; A M Svennerholm
Journal:  Scand J Gastroenterol       Date:  2001-10       Impact factor: 2.423

9.  Secretory leukocyte protease inhibitor mediates proliferation of human endometrial epithelial cells by positive and negative regulation of growth-associated genes.

Authors:  Daying Zhang; Rosalia C M Simmen; Frank J Michel; Ge Zhao; Dustin Vale-Cruz; Frank A Simmen
Journal:  J Biol Chem       Date:  2002-05-22       Impact factor: 5.157

10.  Secretory leucoprotease inhibitor prevents lipopolysaccharide-induced IkappaBalpha degradation without affecting phosphorylation or ubiquitination.

Authors:  Clifford C Taggart; Catherine M Greene; Noel G McElvaney; Shane O'Neill
Journal:  J Biol Chem       Date:  2002-06-25       Impact factor: 5.157
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  3 in total

1.  Mucosal Progranulin expression is induced by H. pylori, but independent of Secretory Leukocyte Protease Inhibitor (SLPI) expression.

Authors:  Thomas Wex; Doerthe Kuester; Cornelius Schönberg; Daniel Schindele; Gerhard Treiber; Peter Malfertheiner
Journal:  BMC Gastroenterol       Date:  2011-05-26       Impact factor: 3.067

2.  Expression QTL mapping in regulatory and helper T cells from the BXD family of strains reveals novel cell-specific genes, gene-gene interactions and candidate genes for auto-immune disease.

Authors:  Rudi Alberts; Hairong Chen; Claudia Pommerenke; August B Smit; Sabine Spijker; Robert W Williams; Robert Geffers; Dunja Bruder; Klaus Schughart
Journal:  BMC Genomics       Date:  2011-12-19       Impact factor: 3.969

3.  The Host Cell Transcription Factor EGR1 Is Induced by Bacteria through the EGFR-ERK1/2 Pathway.

Authors:  Nele de Klerk; Sunil D Saroj; Gabriela M Wassing; Lisa Maudsdotter; Ann-Beth Jonsson
Journal:  Front Cell Infect Microbiol       Date:  2017-01-25       Impact factor: 5.293
  3 in total

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