Literature DB >> 15039363

The hydrophobic domain of the Mycobacterial Erp protein is not essential for the virulence of Mycobacterium tuberculosis.

Dana Kocíncová1, Berit Sondén, Yann Bordat, Elisabeth Pivert, Leila de Mendonça-Lima, Brigitte Gicquel, Jean-Marc Reyrat.   

Abstract

Erp (exported repetitive protein) is a member of a mycobacterium-specific family of extracellular proteins. A hydrophobic region that is localized at the C-terminal domain and that represents a quarter of the protein is highly conserved across species. Here we show that this hydrophobic region is not essential for restoring the virulence and tissue damage of an erp::aph mutant strain of M. tuberculosis as assessed by bacterial counts and lung histology analysis in a mouse model of tuberculosis.

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Year:  2004        PMID： 15039363      PMCID： PMC375180          DOI： 10.1128/IAI.72.4.2379-2382.2004

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  20 in total

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2.  Analysis of the phthiocerol dimycocerosate locus of Mycobacterium tuberculosis. Evidence that this lipid is involved in the cell wall permeability barrier.

Authors:  L R Camacho; P Constant; C Raynaud; M A Laneelle; J A Triccas; B Gicquel; M Daffe; C Guilhot
Journal:  J Biol Chem       Date:  2001-03-13       Impact factor: 5.157

3.  Massive gene decay in the leprosy bacillus.

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Journal:  Nature       Date:  2001-02-22       Impact factor: 49.962

4.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

5.  Erp, an extracellular protein family specific to mycobacteria.

Authors:  Leila de Mendonça-Lima; Mathieu Picardeau; Catherine Raynaud; Jean Rauzier; Yves-Olivier Goguet de la Salmonière; Lucia Barker; Fabiana Bigi; Angel Cataldi; Brigitte Gicquel; Jean-Marc Reyrat
Journal:  Microbiology       Date:  2001-08       Impact factor: 2.777

6.  A novel mycolic acid cyclopropane synthetase is required for cording, persistence, and virulence of Mycobacterium tuberculosis.

Authors:  M S Glickman; J S Cox; W R Jacobs
Journal:  Mol Cell       Date:  2000-04       Impact factor: 17.970

Review 7.  Mycobacterium tuberculosis pathogenesis and molecular determinants of virulence.

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Journal:  Clin Microbiol Rev       Date:  2003-07       Impact factor: 26.132

8.  The allele encoding the mycobacterial Erp protein affects lung disease in mice.

Authors:  Leila de Mendonça-Lima; Yann Bordat; Elisabeth Pivert; Chiara Recchi; Olivier Neyrolles; Aboubakar Maitournam; Brigitte Gicquel; Jean-Marc Reyrat
Journal:  Cell Microbiol       Date:  2003-01       Impact factor: 3.715

9.  Identification of mycobacterium tuberculosis DNA sequences encoding exported proteins by using phoA gene fusions.

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Journal:  J Bacteriol       Date:  1995-01       Impact factor: 3.490

10.  Reduced immunopathology and mortality despite tissue persistence in a Mycobacterium tuberculosis mutant lacking alternative sigma factor, SigH.

Authors:  Deepak Kaushal; Benjamin G Schroeder; Sandeep Tyagi; Tetsuyuki Yoshimatsu; Cherise Scott; Chiew Ko; Liane Carpenter; Jyoti Mehrotra; Yukari C Manabe; Robert D Fleischmann; William R Bishai
Journal:  Proc Natl Acad Sci U S A       Date:  2002-06-11       Impact factor: 11.205
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  4 in total

1.  Biochemical disclosure of the mycolate outer membrane of Corynebacterium glutamicum.

Authors:  Christophe H Marchand; Christophe Salmeron; Roland Bou Raad; Xavier Méniche; Mohamed Chami; Muriel Masi; Didier Blanot; Mamadou Daffé; Marielle Tropis; Emilie Huc; Pierre Le Maréchal; Paulette Decottignies; Nicolas Bayan
Journal:  J Bacteriol       Date:  2011-11-28       Impact factor: 3.490

2.  Mycobacterium marinum Erp is a virulence determinant required for cell wall integrity and intracellular survival.

Authors:  Christine L Cosma; Kathryn Klein; Rosa Kim; Dana Beery; Lalita Ramakrishnan
Journal:  Infect Immun       Date:  2006-06       Impact factor: 3.441

3.  Novel In Silico Insights into Rv1417 and Rv2617c as Potential Protein Targets: The Importance of the Medium on the Structural Interactions with Exported Repetitive Protein (Erp) of Mycobacterium tuberculosis.

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Journal:  Polymers (Basel)       Date:  2022-06-25       Impact factor: 4.967

4.  Identification of two proteins that interact with the Erp virulence factor from Mycobacterium tuberculosis by using the bacterial two-hybrid system.

Authors:  Laura I Klepp; Marcelo Soria; Federico C Blanco; María V Bianco; María P Santangelo; Angel A Cataldi; Fabiana Bigi
Journal:  BMC Mol Biol       Date:  2009-01-21       Impact factor: 2.946
  4 in total

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