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Literature DB >> 15039203

Building a more perfect beast: APP transgenic mice with neuronal loss.

Dennis W Dickson¹.

Abstract

Entities: Disease Species

Mesh：

Substances：

Year: 2004 PMID： 15039203 PMCID： PMC1615338 DOI： 10.1016/S0002-9440(10)63202-6

Source DB: PubMed Journal: Am J Pathol ISSN： 0002-9440 Impact factor: 4.307

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26 in total

1. Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein.

Authors: J Lewis; E McGowan; J Rockwood; H Melrose; P Nacharaju; M Van Slegtenhorst; K Gwinn-Hardy; M Paul Murphy; M Baker; X Yu; K Duff; J Hardy; A Corral; W L Lin; S H Yen; D W Dickson; P Davies; M Hutton
Journal: Nat Genet Date: 2000-08 Impact factor: 38.330

2. Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695.

Authors: M A Chishti; D S Yang; C Janus; A L Phinney; P Horne; J Pearson; R Strome; N Zuker; J Loukides; J French; S Turner; G Lozza; M Grilli; S Kunicki; C Morissette; J Paquette; F Gervais; C Bergeron; P E Fraser; G A Carlson; P S George-Hyslop; D Westaway
Journal: J Biol Chem Date: 2001-03-15 Impact factor: 5.157

3. Augmented senile plaque load in aged female beta-amyloid precursor protein-transgenic mice.

Authors: M J Callahan; W J Lipinski; F Bian; R A Durham; A Pack; L C Walker
Journal: Am J Pathol Date: 2001-03 Impact factor: 4.307

4. Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: lack of association with amyloid deposits.

Authors: L A Holcomb; M N Gordon; P Jantzen; K Hsiao; K Duff; D Morgan
Journal: Behav Genet Date: 1999-05 Impact factor: 2.805

5. Accelerated plaque accumulation, associative learning deficits, and up-regulation of alpha 7 nicotinic receptor protein in transgenic mice co-expressing mutant human presenilin 1 and amyloid precursor proteins.

Authors: Kelly T Dineley; Xuefeng Xia; Duy Bui; J David Sweatt; Hui Zheng
Journal: J Biol Chem Date: 2002-03-23 Impact factor: 5.157

Review 6. Developing mouse models of aging: a consideration of strain differences in age-related behavioral and neural parameters.

Authors: D K Ingram; M Jucker
Journal: Neurobiol Aging Date: 1999 Mar-Apr Impact factor: 4.673

7. Plaque-induced abnormalities in neurite geometry in transgenic models of Alzheimer disease: implications for neural system disruption.

Authors: R Le; L Cruz; B Urbanc; R B Knowles; K Hsiao-Ashe; K Duff; M C Irizarry; H E Stanley; B T Hyman
Journal: J Neuropathol Exp Neurol Date: 2001-08 Impact factor: 3.685

8. Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss.

Authors: A Takeuchi; M C Irizarry; K Duff; T C Saido; K Hsiao Ashe; M Hasegawa; D M Mann; B T Hyman; T Iwatsubo
Journal: Am J Pathol Date: 2000-07 Impact factor: 4.307

9. Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models.

Authors: A Y Hsia; E Masliah; L McConlogue; G Q Yu; G Tatsuno; K Hu; D Kholodenko; R C Malenka; R A Nicoll; L Mucke
Journal: Proc Natl Acad Sci U S A Date: 1999-03-16 Impact factor: 11.205

10. Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease.

Authors: T Kawarabayashi; L H Younkin; T C Saido; M Shoji; K H Ashe; S G Younkin
Journal: J Neurosci Date: 2001-01-15 Impact factor: 6.167

7 in total

1. Massive CA1/2 neuronal loss with intraneuronal and N-terminal truncated Abeta42 accumulation in a novel Alzheimer transgenic model.

Authors: Caty Casas; Nicolas Sergeant; Jean-Michel Itier; Véronique Blanchard; Oliver Wirths; Nicolien van der Kolk; Valérie Vingtdeux; Evita van de Steeg; Gwenaëlle Ret; Thierry Canton; Hervé Drobecq; Allan Clark; Bruno Bonici; André Delacourte; Jesús Benavides; Christoph Schmitz; Günter Tremp; Thomas A Bayer; Patrick Benoit; Laurent Pradier
Journal: Am J Pathol Date: 2004-10 Impact factor: 4.307

2. BACE1 gene deletion prevents neuron loss and memory deficits in 5XFAD APP/PS1 transgenic mice.

Authors: Masuo Ohno; Sarah L Cole; Marina Yasvoina; Jie Zhao; Martin Citron; Robert Berry; John F Disterhoft; Robert Vassar
Journal: Neurobiol Dis Date: 2006-12-20 Impact factor: 5.996

3. Hippocampal interneuron loss in an APP/PS1 double mutant mouse and in Alzheimer's disease.

Authors: Hisaaki Takahashi; Ivona Brasnjevic; Bart P F Rutten; Nicolien Van Der Kolk; Daniel P Perl; Constantin Bouras; Harry W M Steinbusch; Christoph Schmitz; Patrick R Hof; Dara L Dickstein
Journal: Brain Struct Funct Date: 2010-03-07 Impact factor: 3.270

4. Age-related loss of synaptophysin immunoreactive presynaptic boutons within the hippocampus of APP751SL, PS1M146L, and APP751SL/PS1M146L transgenic mice.

Authors: Bart P F Rutten; Nicolien M Van der Kolk; Stephanie Schafer; Marc A M J van Zandvoort; Thomas A Bayer; Harry W M Steinbusch; Christoph Schmitz
Journal: Am J Pathol Date: 2005-07 Impact factor: 4.307