Literature DB >> 15038975

Unique function of the Nrf2-Keap1 pathway in the inducible expression of antioxidant and detoxifying enzymes.

Akira Kobayashi1, Tsutomu Ohta, Masayuki Yamamoto.   

Abstract

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Year:  2004        PMID： 15038975     DOI： 10.1016/S0076-6879(04)78021-0

Source DB:  PubMed          Journal:  Methods Enzymol        ISSN： 0076-6879            Impact factor:   1.600


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  83 in total

1.  Coordinated regulation of Nrf2 and histone H3 serine 10 phosphorylation in arsenite-activated transcription of the human heme oxygenase-1 gene.

Authors:  Paul D Ray; Bo-Wen Huang; Yoshiaki Tsuji
Journal:  Biochim Biophys Acta       Date:  2015-08-18

2.  NRF2 antioxidant response protects against acidic bile salts-induced oxidative stress and DNA damage in esophageal cells.

Authors:  Dunfa Peng; Heng Lu; Shoumin Zhu; Zhangjian Zhou; Tianling Hu; Zheng Chen; Alexander Zaika; Wael El-Rifai
Journal:  Cancer Lett       Date:  2019-05-24       Impact factor: 8.679

3.  Keap1 regulates the oxidation-sensitive shuttling of Nrf2 into and out of the nucleus via a Crm1-dependent nuclear export mechanism.

Authors:  Michaella Velichkova; Tama Hasson
Journal:  Mol Cell Biol       Date:  2005-06       Impact factor: 4.272

4.  In Vitro Biotransformation of the Nrf2 Activator Bardoxolone: Formation of an Epoxide Metabolite That Undergoes Two Novel Glutathione-Mediated Metabolic Pathways: Epoxide Reduction and Oxidative Elimination of Nitrile Moiety.

Authors:  Amin M Kamel; Stephen Bowlin; Ban Anwar; Holly Reichard; Joe Argus; Ian A Blair
Journal:  Chem Res Toxicol       Date:  2019-10-25       Impact factor: 3.739

5.  A muscle-specific p38 MAPK/Mef2/MnSOD pathway regulates stress, motor function, and life span in Drosophila.

Authors:  Alysia Vrailas-Mortimer; Tania del Rivero; Subhas Mukherjee; Sanjay Nag; Alexandros Gaitanidis; Dimitris Kadas; Christos Consoulas; Atanu Duttaroy; Subhabrata Sanyal
Journal:  Dev Cell       Date:  2011-10-18       Impact factor: 12.270

6.  Negative regulation of the Nrf1 transcription factor by its N-terminal domain is independent of Keap1: Nrf1, but not Nrf2, is targeted to the endoplasmic reticulum.

Authors:  Yiguo Zhang; Dorothy H Crouch; Masayuki Yamamoto; John D Hayes
Journal:  Biochem J       Date:  2006-11-01       Impact factor: 3.857

7.  Nrf2 protects human bladder urothelial cells from arsenite and monomethylarsonous acid toxicity.

Authors:  Xiao-Jun Wang; Zheng Sun; Weimin Chen; Kylee E Eblin; Jay A Gandolfi; Donna D Zhang
Journal:  Toxicol Appl Pharmacol       Date:  2007-08-07       Impact factor: 4.219

8.  Antioxidant responses and NRF2 in synergistic developmental toxicity of PAHs in zebrafish.

Authors:  Alicia R Timme-Laragy; Lindsey A Van Tiem; Elwood A Linney; Richard T Di Giulio
Journal:  Toxicol Sci       Date:  2009-02-20       Impact factor: 4.849

9.  Essential roles of the PI3 kinase/Akt pathway in regulating Nrf2-dependent antioxidant functions in the RPE.

Authors:  Ling Wang; Yan Chen; Paul Sternberg; Jiyang Cai
Journal:  Invest Ophthalmol Vis Sci       Date:  2008-04       Impact factor: 4.799

10.  Identification and Characterization of MCM3 as a Kelch-like ECH-associated Protein 1 (KEAP1) Substrate.

Authors:  Kathleen M Mulvaney; Jacob P Matson; Priscila F Siesser; Tigist Y Tamir; Dennis Goldfarb; Timothy M Jacobs; Erica W Cloer; Joseph S Harrison; Cyrus Vaziri; Jeanette G Cook; Michael B Major
Journal:  J Biol Chem       Date:  2016-09-12       Impact factor: 5.157
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