| Literature DB >> 15036901 |
Irun R Cohen1, Uri Hershberg, Sorin Solomon.
Abstract
This paper discusses some consequences of the discovery that antigen receptors are degenerate: Immune specificity, in contrast to the tenets of the clonal selection paradigm, must be generated by the immune response down-stream of initial antigen recognition; and specificity is a property of a collective of cells and not of single clones.Mesh：
Substances：
Year: 2004 PMID： 15036901 DOI： 10.1016/j.molimm.2003.11.020
Source DB: PubMed Journal: Mol Immunol ISSN： 0161-5890 Impact factor: 4.407