Literature DB >> 15036856

Multi-channel intracavitary vaginal brachytherapy using three-dimensional optimization of source geometry.

Kari Tanderup1, Jacob C Lindegaard.   

Abstract

BACKGROUND AND
PURPOSE: A new multi-channel vaginal cylinder has been constructed. The dose distribution is compared to that of a central channel cylinder. PATIENTS AND METHODS: The source channels of the multi-channel cylinder are placed close to the treatment volume, which means that the dose gradient in the radial direction is steep. Therefore the dose is enhanced close to the cylinder surface and lowered at larger distances as compared to the central channel cylinder. Three patients were each CT-scanned twice with a vaginal cylinder in situ. CT-based 3D dose-planning studies were used to calculate the dose distribution. Dose-volume histograms (DVHs) were generated for rectum and bladder, and a quantification of high dose volumes was calculated from the DVHs. Dose to the vaginal mucosa was calculated.
RESULTS: The dose to the critical organs depends on the depth of normalization. When the dose is normalized on the cylinder surface the hot spot dose to bladder and rectum is reduced by 16 and 17%, respectively, whereas mucosal dose remains the same. When the dose is normalized at 5 mm depth the hot spot dose to bladder and rectum is reduced by 1 and 3%, respectively, whereas mucosal dose is enhanced by 17%.
CONCLUSIONS: The multi-channel cylinder makes it possible to spare the rectum and the bladder at the expense of enhanced mucosal dose.

Entities:  

Mesh:

Year:  2004        PMID: 15036856     DOI: 10.1016/j.radonc.2003.11.006

Source DB:  PubMed          Journal:  Radiother Oncol        ISSN: 0167-8140            Impact factor:   6.280


  9 in total

Review 1.  American Brachytherapy Task Group Report: Adjuvant vaginal brachytherapy for early-stage endometrial cancer: A comprehensive review.

Authors:  Matthew M Harkenrider; Alec M Block; Kaled M Alektiar; David K Gaffney; Ellen Jones; Ann Klopp; Akila N Viswanathan; William Small
Journal:  Brachytherapy       Date:  2016-05-31       Impact factor: 2.362

2.  Single versus multichannel applicator in high-dose-rate vaginal brachytherapy optimized by inverse treatment planning.

Authors:  Yasir A Bahadur; Camelia Constantinescu; Ashraf H Hassouna; Maha M Eltaher; Noor M Ghassal; Nesreen A Awad
Journal:  J Contemp Brachytherapy       Date:  2014-12-31

3.  A novel intracavitary applicator design for the treatment of deep vaginal fornices: preliminary dose metrics and geometric analysis.

Authors:  Antonio L Damato; Robert A Cormack; Akila N Viswanathan
Journal:  J Contemp Brachytherapy       Date:  2015-02-13

4.  A comparison between 2D and 3D planning of high-dose-rate vaginal cuff brachytherapy in patients with stage I-II endometrial cancer using cobalt-60.

Authors:  Farnaz Amouzegar Hashemi; Sepideh Mansouri; Mahdi Aghili; Ebrahim Esmati; Mohammad Babaei; Arefeh Saeedian; Sepand Moalej; Ramin Jaberi
Journal:  J Contemp Brachytherapy       Date:  2021-10-25

5.  Use of a Flexible Inflatable Multi-Channel Applicator for Vaginal Brachytherapy in the Management of Gynecologic Cancer.

Authors:  Samuel M Shin; Tamara L Duckworth; Benjamin T Cooper; John P Curtin; Peter B Schiff; J Keith DeWyngaert; Stella C Lymberis
Journal:  Front Oncol       Date:  2015-09-14       Impact factor: 6.244

6.  Feasibility study and optimum loading pattern of a multi-ring inflatable intravaginal applicator.

Authors:  Hsiang-Chi Kuo; Keyur J Mehta; Ravindra Yaparpalvi; Linda Hong; Dinesh Mynampati; Wolfgang A Tomé; Shalom Kalnicki
Journal:  J Contemp Brachytherapy       Date:  2013-06-28

7.  Treatment planning methodology for the Miami Multichannel Applicator following the American Brachytherapy Society recently published guidelines: the Lahey Clinic experience.

Authors:  Ileana Iftimia; Eileen T Cirino; Herbert W Mower; Andrea B McKee
Journal:  J Appl Clin Med Phys       Date:  2013-01-07       Impact factor: 2.102

8.  Bladder and rectum dose estimations on digitized radiographs for vaginal brachytherapy after hysterectomy.

Authors:  Winson Zhang; Sundershan K Bhatia; Wenqing Sun; Joseph M Modrick; Yusung Kim
Journal:  J Appl Clin Med Phys       Date:  2014-11-08       Impact factor: 2.102

9.  3D printer-based novel intensity-modulated vaginal brachytherapy applicator: feasibility study.

Authors:  Fatih Biltekin; Husnu Fadil Akyol; Melis Gültekin; Ferah Yildiz
Journal:  J Contemp Brachytherapy       Date:  2020-02-28
  9 in total

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