Literature DB >> 1503670

Adverse reactions to drugs as a cause of admissions to a general teaching hospital in Hong Kong.

T Y Chan1, J C Chan, B Tomlinson, J A Critchley.   

Abstract

To determine the pattern of and the risk factors for adverse drug reactions (ADRs) in Hong Kong, a prospective study of acute admissions to 2 general medical wards at the Prince of Wales Hospital was undertaken. Of the 1701 admissions included in this study, 74 (4.4%) were attributed to ADRs. Sulphonylureas, nonsteroidal anti-inflammatories (NSAIDs) and insulin accounted for 61% of cases. The most frequent ADRs were hypoglycaemia (43%) and gastrointestinal haemorrhage (29.7%). Both old age and impaired renal function appear to be important risk factors for ADRs. In such situations, careful dose adjustments, use of an alternative drug or total avoidance may be necessary. Particular attention should be given to oral hypoglycaemic drugs and NSAIDs.

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Year:  1992        PMID： 1503670     DOI： 10.2165/00002018-199207030-00008

Source DB:  PubMed          Journal:  Drug Saf        ISSN： 0114-5916            Impact factor:   5.606


  15 in total

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Journal:  Diabetologia       Date:  1987-11       Impact factor: 10.122

10.  [The relatively frequent incidence of severe sulfonylurea-induced hypoglycemia in the last 25 years in Switzerland. Results of 2 surveys in Switzerland in 1969 and 1984].

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Journal:  Schweiz Med Wochenschr       Date:  1986-02-01
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  10 in total

1.  Lack of awareness of community-acquired adverse drug reactions upon hospital admission : dimensions and consequences of a dilemma.

Authors:  Harald Dormann; Manfred Criegee-Rieck; Antje Neubert; Tobias Egger; Arnim Geise; Sabine Krebs; Thomas Schneider; Micha Levy; Eckhart Hahn; Kay Brune
Journal:  Drug Saf       Date:  2003       Impact factor: 5.606

Review 2.  Drug-induced disorders of glucose metabolism. Mechanisms and management.

Authors:  J C Chan; C S Cockram; J A Critchley
Journal:  Drug Saf       Date:  1996-08       Impact factor: 5.606

Review 3.  Age-related changes in the gastrointestinal system. Effects on drug therapy.

Authors:  F L Iber; P A Murphy; E S Connor
Journal:  Drugs Aging       Date:  1994-07       Impact factor: 3.923

Review 4.  Repaglinide: a review of its therapeutic use in type 2 diabetes mellitus.

Authors:  C R Culy; B Jarvis
Journal:  Drugs       Date:  2001       Impact factor: 9.546

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Authors:  N Moore; D Lecointre; C Noblet; M Mabille
Journal:  Br J Clin Pharmacol       Date:  1998-03       Impact factor: 4.335

6.  Adverse drug reactions in adult medical inpatients in a South African hospital serving a community with a high HIV/AIDS prevalence: prospective observational study.

Authors:  Ushma Mehta; David N Durrheim; Marc Blockman; Tamara Kredo; Ronald Gounden; Karen I Barnes
Journal:  Br J Clin Pharmacol       Date:  2007-12-07       Impact factor: 4.335

7.  Poisoning due to an over-the-counter hypnotic, Sleep-Qik (hyoscine, cyproheptadine, valerian).

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Journal:  Postgrad Med J       Date:  1995-04       Impact factor: 2.401

8.  Adverse drug reactions caused by drug-drug interactions reported to Croatian Agency for Medicinal Products and Medical Devices: a retrospective observational study.

Authors:  Nikica Mirosevic Skvrce; Viola Macolic Sarinic; Iva Mucalo; Darko Krnic; Nada Bozina; Sinisa Tomic
Journal:  Croat Med J       Date:  2011-10-15       Impact factor: 1.351

9.  Adverse drug reaction monitoring in a tertiary care teaching hospital.

Authors:  Shalini Chawla; Bhupinder Singh Kalra; Pinky Dharmshaktu; Pooja Sahni
Journal:  J Pharmacol Pharmacother       Date:  2011-07

Review 10.  Herbal Medicines Induced Anticholinergic Poisoning in Hong Kong.

Authors:  Thomas Y K Chan
Journal:  Toxins (Basel)       Date:  2016-03-18       Impact factor: 4.546
  10 in total

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