| Literature DB >> 15036661 |
Yoshimitsu Niwa1, Nobuyuki Hamajima, Yoshiko Atsuta, Kazuhito Yamamoto, Akiko Tamakoshi, Toshiko Saito, Kaoru Hirose, Toru Nakanishi, Akihiro Nawa, Kazuo Kuzuya, Kazuo Tajima.
Abstract
To examine the possible association between cervical cancer and p73 G4C14-to-A4T14 in exon 2 and p53 Arg72Pro polymorphisms, an incident case-control study was conducted in Japanese. The cases were 112 cervical cancer patients. Controls were 320 healthy women and 122 non-cancer female outpatients. Risk estimation for each genotype by an unconditional logistic model demonstrated a possible association between the p73 A4T14 variant and the risk of cervical cancer in our Japanese population (OR = 1.57; 95%CI, 0.99-2.48, P = 0.053). There was no significant difference in the p53 Arg72Pro genotype frequency between the controls and cases.Entities:
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Year: 2004 PMID： 15036661 DOI： 10.1016/j.canlet.2003.11.014
Source DB: PubMed Journal: Cancer Lett ISSN： 0304-3835 Impact factor: 8.679