Literature DB >> 15036475

Evaluation of hypoglycemic and antihyperglycemic effects of Datura metel (Linn.) seeds in normal and alloxan-induced diabetic rats.

B Krishna Murthy1, S Nammi, M K Kota, R V Krishna Rao, N Koteswara Rao, A Annapurna.   

Abstract

The seed powder of Datura metel was tested for its hypoglycemic activity in normal and alloxan-induced diabetic rats. Graded doses (25, 50 and 75 mg/kg, p.o.) of the seed powder when given to both normal and diabetic rats produced significant reduction in blood glucose at the 8 h. The effect was found to be dose dependent with all treatments at the doses administered.

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Year:  2004        PMID: 15036475     DOI: 10.1016/j.jep.2003.12.010

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN: 0378-8741            Impact factor:   4.360


  17 in total

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Journal:  Environ Sci Pollut Res Int       Date:  2017-07-28       Impact factor: 4.223

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Authors:  Stephen O Adewole; John A O Ojewole
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4.  In vivo Antidiabetic and Antioxidant Potential of Stephania hernandifolia in Streptozotocin-Induced-Diabetic Rats.

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5.  Hypoglycaemic and anti-diabetic activity of stem bark extracts Erythrina indica in normal and alloxan-induced diabetic rats.

Authors:  A Yashwant Kumar; K Nandakumar; M Handral; Sahil Talwar; Daniel Dhayabaran
Journal:  Saudi Pharm J       Date:  2010-10-31       Impact factor: 4.330

6.  Evaluation of Antidiabetic and Antioxidant Potential of Hydromethanolic Seed Extract of Datura stramonium Linn (Solanaceae).

Authors:  Bamlaku Cherie Melaku; Gedefaw Getnet Amare
Journal:  J Exp Pharmacol       Date:  2020-06-22

7.  Antihyperglycemic and antihyperlipidemic activity of plectranthus amboinicus on normal and alloxan-induced diabetic rats.

Authors:  A H M Viswanathaswamy; B C Koti; Aparna Gore; A H M Thippeswamy; R V Kulkarni
Journal:  Indian J Pharm Sci       Date:  2011-03       Impact factor: 0.975

8.  Isolation of biologically active constituents from Moringa peregrina (Forssk.) Fiori. (family: Moringaceae) growing in Egypt.

Authors:  Taha S El-Alfy; Shahira M Ezzat; Ahmed K Hegazy; Aziza M M Amer; Gehan M Kamel
Journal:  Pharmacogn Mag       Date:  2011-04       Impact factor: 1.085

9.  Effect of ethanolic extract of Cryptolepis sanguinolenta stem on in vivo and in vitro glucose absorption and transport: Mechanism of its antidiabetic activity.

Authors:  A F Ajayi; R E Akhigbe; O M Adewumi; L O Okeleji; K B Mujaidu; S B Olaleye
Journal:  Indian J Endocrinol Metab       Date:  2012-03

10.  Drug-drug interaction between voriconazole and oral hypoglycemic agents in diabetic rats.

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Journal:  Indian J Pharmacol       Date:  2013 Mar-Apr       Impact factor: 1.200

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