| Literature DB >> 15036462 |
N Rajendra Prasad1, C Anandi, S Balasubramanian, K V Pugalendi.
Abstract
Extracts obtained from seeds of Psoralea corylifolia showed several degrees of antifungal activity against Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum and Microsporum gypseum by the disc diffusion method on a Sabouraud dextrose agar (SDA) medium. Methanol extract of the seeds at 250 microg exhibited the maximum inhibition with a halo of 28 mm diameter. Six different bands were obtained when the methanol extract was subjected to TLC. 13C NMR and Mass spectra revealed that the active compound would be a flavonoid, 4'-methoxy flavone. MIC of the active compound along with standard miconazole was carried out using tube dilution technique.Entities:
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Year: 2004 PMID： 15036462 DOI： 10.1016/j.jep.2003.11.010
Source DB: PubMed Journal: J Ethnopharmacol ISSN： 0378-8741 Impact factor: 4.360