Literature DB >> 15036272

A mechanistic model for the aging of human skin.

Paolo U Giacomoni1, Glen Rein.   

Abstract

The microinflammatory model of skin aging is described. This model accounts for the loss of elasticity, resiliene and flexibility of the dermis, as well as for the appearance of wrinkles and for the thinning of the epidermis which are associated with aging. The lack of appropriate apparatuses for the correct measurements of skin hydration does not allow one to test this model for its predictive capability of the appearance of dry skin with age. The micro-inflammatory model of skin aging fails to predict the appearance of age spots on the surface of the skin.

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Year:  2004        PMID： 15036272     DOI： 10.1016/j.micron.2003.11.004

Source DB:  PubMed          Journal:  Micron        ISSN： 0968-4328            Impact factor:   2.251


  7 in total

1.  Ageing, science and the cosmetics industry. The micro-inflammatory model serves as a basis for developing effective anti-ageing products for the skin.

Authors:  Paolo U Giacomoni
Journal:  EMBO Rep       Date:  2005-07       Impact factor: 8.807

2.  Resveratrol prevents oxidative stress-induced senescence and proliferative dysfunction by activating the AMPK-FOXO3 cascade in cultured primary human keratinocytes.

Authors:  Yasuo Ido; Albert Duranton; Fan Lan; Karen A Weikel; Lionel Breton; Neil B Ruderman
Journal:  PLoS One       Date:  2015-02-03       Impact factor: 3.240

Review 3.  An overview about oxidation in clinical practice of skin aging.

Authors:  Silas Arandas Monteiro E Silva; Bozena Michniak-Kohn; Gislaine Ricci Leonardi
Journal:  An Bras Dermatol       Date:  2017 May-Jun       Impact factor: 1.896

4.  Coenzyme Q10 Efficacy Test for Human Skin Equivalents Using a Pumpless Skin-On-A-Chip System.

Authors:  Jisue Kim; Kyunghee Kim; Gun Yong Sung
Journal:  Int J Mol Sci       Date:  2020-11-11       Impact factor: 5.923

5.  The novel PPAR α/γ dual agonist MHY 966 modulates UVB-induced skin inflammation by inhibiting NF-κB activity.

Authors:  Min Hi Park; Ji Young Park; Hye Jin Lee; Dae Hyun Kim; Ki Wung Chung; Daeui Park; Hyoung Oh Jeong; Hye Rim Kim; Chan Hum Park; So Ra Kim; Pusoon Chun; Youngjoo Byun; Hyung Ryong Moon; Hae Young Chung
Journal:  PLoS One       Date:  2013-10-09       Impact factor: 3.240

6.  Improvements in Skin Quality Biological Markers in Skin Explants Using Hyaluronic Acid Filler VYC-12L.

Authors:  Lauren Nakab; Christopher K Hee; Olivier Guetta
Journal:  Plast Reconstr Surg Glob Open       Date:  2020-03-27

Review 7.  Development of Skin-On-A-Chip Platforms for Different Utilizations: Factors to Be Considered.

Authors:  J Ponmozhi; S Dhinakaran; Zsófia Varga-Medveczky; Katalin Fónagy; Luca Anna Bors; Kristóf Iván; Franciska Erdő
Journal:  Micromachines (Basel)       Date:  2021-03-10       Impact factor: 2.891
  7 in total

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