R T Hoffmann1, T F Jakobs, M F Reiser, T K Helmberger. 1. Institut für Klinische Radiologie, Klinikum Grosshadern der Universität München. ralf-thorsten.hoffmann@ikra.med.uni-muenchen.de
Abstract
BACKGROUND AND PURPOSE: Radiofrequency ablation is increasingly used to treat tumors "beyond the liver". The aim of this article is to perform a structured and critical review of the current literature concerning RFA of the lung and to compare these results with our own experience. MATERIAL AND METHODS: 16 patients with tumors or metastases of the lung were treated in our institution within 18 months. 8 of these 16 patients were treated in a multicenter trial. For this article we compared our results to the results of all publications concerning RFA of the lung since 1995. RESULTS: 8 of our 16 patients were not included in the international multicenter trial and were followed-up at least 15 months. Within this observation period, 2 of 8 patients had recurrence of the tumors while in 6 patients no recurrence was detected. Lee et al. published a study with 30 patients. In 10 of these 30 patients RFA was performed in a curative intention with a therapeutical success in 8 of 10 patients after one year. DISCUSSION: Radiofrequency ablation of lung tumors smaller than 3 cm appears to be an alternative to surgical removal. Moreover, RFA offers a higher quality of life for the patients due to a low morbidity and mortality. However, more studies with longer observation periods are necessary for a definite conclusions.
BACKGROUND AND PURPOSE: Radiofrequency ablation is increasingly used to treat tumors "beyond the liver". The aim of this article is to perform a structured and critical review of the current literature concerning RFA of the lung and to compare these results with our own experience. MATERIAL AND METHODS: 16 patients with tumors or metastases of the lung were treated in our institution within 18 months. 8 of these 16 patients were treated in a multicenter trial. For this article we compared our results to the results of all publications concerning RFA of the lung since 1995. RESULTS: 8 of our 16 patients were not included in the international multicenter trial and were followed-up at least 15 months. Within this observation period, 2 of 8 patients had recurrence of the tumors while in 6 patients no recurrence was detected. Lee et al. published a study with 30 patients. In 10 of these 30 patients RFA was performed in a curative intention with a therapeutical success in 8 of 10 patients after one year. DISCUSSION: Radiofrequency ablation of lung tumors smaller than 3 cm appears to be an alternative to surgical removal. Moreover, RFA offers a higher quality of life for the patients due to a low morbidity and mortality. However, more studies with longer observation periods are necessary for a definite conclusions.
Authors: David S K Lu; Steven S Raman; Darko J Vodopich; Michael Wang; James Sayre; Charles Lassman Journal: AJR Am J Roentgenol Date: 2002-01 Impact factor: 3.959
Authors: Bradford J Wood; Jeffrey R Ramkaransingh; Tito Fojo; McClellan M Walther; Stephen K Libutti Journal: Cancer Date: 2002-01-15 Impact factor: 6.860
Authors: Jeong Min Lee; Sang Won Kim; Chun Ai Li; Ji Hyun Youk; Young Kon Kim; Zhewu Jin; Myoung Ja Chung; Mi Suk Lee Journal: Korean J Radiol Date: 2002 Oct-Dec Impact factor: 3.500