Literature DB >> 15033735

Thallium induces apoptosis in Jurkat cells.

Marcantonio Bragadin1, Antonio Toninello, Alberto Bindoli, Maria Pia Rigobello, Marcella Canton.   

Abstract

Thallium induces swelling in mitochondria and apoptosis in Jurkat cells. Both the swelling and the apoptosis are inhibited by means of cyclosporine A (CsA), thus suggesting that these phenomena result from the opening of the membrane transition pore (MTP) in mitochondria. Therefore, apoptosis can be explained as due to the opening of the MTP in mitochondria.

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Year:  2003        PMID： 15033735     DOI： 10.1196/annals.1299.049

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


  6 in total

1.  A study on the concentration of heavy metals and histopathological changes in Persian jirds (Mammals; Rodentia), affected by mining activities in an iron ore mine in Iran.

Authors:  Amir Shahsavari; Fatemeh Tabatabaei Yazdi; Zahra Moosavi; Ava Heidari; Pourya Sardari
Journal:  Environ Sci Pollut Res Int       Date:  2019-03-09       Impact factor: 4.223

2.  Influence of Tl(+) on mitochondrial permeability transition pore in Ca(2+)-loaded rat liver mitochondria.

Authors:  Sergey M Korotkov; Nils-Erik L Saris
Journal:  J Bioenerg Biomembr       Date:  2011-03-19       Impact factor: 2.945

3.  Effects of Tl(+) on ion permeability, membrane potential and respiration of isolated rat liver mitochondria.

Authors:  Sergey M Korotkov
Journal:  J Bioenerg Biomembr       Date:  2009-07-22       Impact factor: 2.945

4.  A Case-Control Study of Prenatal Thallium Exposure and Low Birth Weight in China.

Authors:  Wei Xia; Xiaofu Du; Tongzhang Zheng; Bin Zhang; Yuanyuan Li; Bryan A Bassig; Aifen Zhou; Youjie Wang; Chao Xiong; Zhengkuan Li; Yuanxiang Yao; Jie Hu; Yanqiu Zhou; Juan Liu; Weiyan Xue; Yue Ma; Xinyun Pan; Yang Peng; Shunqing Xu
Journal:  Environ Health Perspect       Date:  2015-05-22       Impact factor: 9.031

Review 5.  Effects of Tl+ on the inner membrane thiol groups, respiration, and swelling in succinate-energized rat liver mitochondria were modified by thiol reagents.

Authors:  Sergey M Korotkov
Journal:  Biometals       Date:  2021-07-08       Impact factor: 2.949

6.  Environmental Toxin Screening Using Human-Derived 3D Bioengineered Liver and Cardiac Organoids.

Authors:  Steven D Forsythe; Mahesh Devarasetty; Thomas Shupe; Colin Bishop; Anthony Atala; Shay Soker; Aleksander Skardal
Journal:  Front Public Health       Date:  2018-04-16
  6 in total

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