| Literature DB >> 15031097 |
Hisao Ohde1, Kei Shinoda, Takatsune Nishiyama, Hisashi Kado, Yasuhiro Haruta, Yukihiko Mashima, Yoshihisa Oguchi.
Abstract
In humans with albinism, a large percentage of the ganglion cell axons from the temporal retina decussate abnormally in the chiasm and synapse in the contralateral LGN. The aim of this study was to determine whether the misrouting of the optic fibers can be detected by magnetoencephalography (MEG). Visually evoked magnetic fields (VEFs) were recorded from three patients with albinism. After monocular stimulation, the isofield contour maps of the VEFs showed a single current dipole pattern over the contralateral hemisphere in patients with albinism. These results clearly illustrated the reduced uncrossed retinofugal pathway of patients with albinism.Entities:
Mesh：
Year: 2004 PMID： 15031097 DOI： 10.1016/j.visres.2003.12.005
Source DB: PubMed Journal: Vision Res ISSN： 0042-6989 Impact factor: 1.886