Literature DB >> 15030769

Immunobiology of mucosal HIV infection and the basis for development of a new generation of mucosal AIDS vaccines.

Igor M Belyakov1, Jay A Berzofsky.   

Abstract

Mucosal tissues are the primary site of natural HIV transmission and a major reservoir for HIV replication. Targeting immune responses to the mucosal entry site before viral dissemination could protect and also clear viral reservoirs. Recent understanding of mucosal HIV transmission and of chemokines and integrins in mucosal trafficking can aid design of new strategies to enhance AIDS vaccine efficacy.

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Year:  2004        PMID： 15030769     DOI： 10.1016/s1074-7613(04)00053-6

Source DB:  PubMed          Journal:  Immunity        ISSN： 1074-7613            Impact factor:   31.745


  41 in total

1.  Long-lasting humoral and cellular immune responses and mucosal dissemination after intramuscular DNA immunization.

Authors:  Vainav Patel; Antonio Valentin; Viraj Kulkarni; Margherita Rosati; Cristina Bergamaschi; Rashmi Jalah; Candido Alicea; Jacob T Minang; Matthew T Trivett; Claes Ohlen; Jun Zhao; Marjorie Robert-Guroff; Amir S Khan; Ruxandra Draghia-Akli; Barbara K Felber; George N Pavlakis
Journal:  Vaccine       Date:  2010-05-06       Impact factor: 3.641

2.  Transcutaneous immunization induces mucosal CTLs and protective immunity by migration of primed skin dendritic cells.

Authors:  Igor M Belyakov; Scott A Hammond; Jeffrey D Ahlers; Gregory M Glenn; Jay A Berzofsky
Journal:  J Clin Invest       Date:  2004-04       Impact factor: 14.808

Review 3.  Nanomedicine in GI.

Authors:  Hamed Laroui; David S Wilson; Guillaume Dalmasso; Khalid Salaita; Niren Murthy; Shanthi V Sitaraman; Didier Merlin
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2010-12-09       Impact factor: 4.052

4.  Impact of vaccine-induced mucosal high-avidity CD8+ CTLs in delay of AIDS viral dissemination from mucosa.

Authors:  Igor M Belyakov; Vladimir A Kuznetsov; Brian Kelsall; Dennis Klinman; Marcin Moniuszko; Michael Lemon; Phillip D Markham; Ranajit Pal; John D Clements; Mark G Lewis; Warren Strober; Genoveffa Franchini; Jay A Berzofsky
Journal:  Blood       Date:  2005-12-22       Impact factor: 22.113

5.  Durable mucosal simian immunodeficiency virus-specific effector memory T lymphocyte responses elicited by recombinant adenovirus vectors in rhesus monkeys.

Authors:  Hualin Li; Jinyan Liu; Angela Carville; Keith G Mansfield; Diana Lynch; Dan H Barouch
Journal:  J Virol       Date:  2011-09-14       Impact factor: 5.103

6.  New GMP manufacturing processes to obtain thermostable HIV-1 gp41 virosomes under solid forms for various mucosal vaccination routes.

Authors:  Mario Amacker; Charli Smardon; Laura Mason; Jack Sorrell; Kirk Jeffery; Michael Adler; Farien Bhoelan; Olga Belova; Mark Spengler; Beena Punnamoottil; Markus Schwaller; Olivia Bonduelle; Behazine Combadière; Toon Stegmann; Andrew Naylor; Richard Johnson; Desmond Wong; Sylvain Fleury
Journal:  NPJ Vaccines       Date:  2020-05-18       Impact factor: 7.344

7.  Inhibition of HIV-1 transmission in trans from dendritic cells to CD4+ T lymphocytes by natural antibodies to the CRD domain of DC-SIGN purified from breast milk and intravenous immunoglobulins.

Authors:  Mary Requena; Hicham Bouhlal; Nadine Nasreddine; Hela Saidi; Jean-Chrysostome Gody; Sylvie Aubry; Gérard Grésenguet; Michel D Kazatchkine; Rafick-Pierre Sekaly; Laurent Bélec; Hakim Hocini
Journal:  Immunology       Date:  2007-11-10       Impact factor: 7.397

8.  Dynamic T cell migration program provides resident memory within intestinal epithelium.

Authors:  David Masopust; Daniel Choo; Vaiva Vezys; E John Wherry; Jaikumar Duraiswamy; Rama Akondy; Jun Wang; Kerry A Casey; Daniel L Barber; Kim S Kawamura; Kathryn A Fraser; Richard J Webby; Volker Brinkmann; Eugene C Butcher; Kenneth A Newell; Rafi Ahmed
Journal:  J Exp Med       Date:  2010-02-15       Impact factor: 14.307

9.  TLR agonists are highly effective at eliciting functional memory CTLs of effector memory phenotype in peptide immunization.

Authors:  Kendra Smyth; Karla Garcia; Zhifeng Sun; Wenbin Tuo; Zhengguo Xiao
Journal:  Int Immunopharmacol       Date:  2012-11-14       Impact factor: 4.932

Review 10.  Progress on new vaccine strategies against chronic viral infections.

Authors:  Jay A Berzofsky; Jeffrey D Ahlers; John Janik; John Morris; SangKon Oh; Masaki Terabe; Igor M Belyakov
Journal:  J Clin Invest       Date:  2004-08       Impact factor: 14.808
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