Literature DB >> 15028482

Fluoroquinolones: mechanism of action, classification, and development of resistance.

Joseph M Blondeau1.   

Abstract

The fluoroquinolones represent an evolving class of broad-spectrum antimicrobial agents used in the prevention and treatment of a variety of ocular infections; however, resistance to currently available agents in the class has been emerging among ocular pathogens. This article reviews the mechanism of action of existing and new fluoroquinolones and discusses the structure-activity relationship of the fluoroquinolones as it relates to the classification of these compounds. This article also highlights the mechanism of resistance among common ocular pathogens and discusses the potential need for newer fluoroquinolones in ophthalmology.

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Year:  2004        PMID: 15028482     DOI: 10.1016/j.survophthal.2004.01.005

Source DB:  PubMed          Journal:  Surv Ophthalmol        ISSN: 0039-6257            Impact factor:   6.048


  48 in total

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Journal:  Eur J Drug Metab Pharmacokinet       Date:  2011-10-21       Impact factor: 2.441

2.  Pharmacodynamic modeling of in vitro activity of marbofloxacin against Escherichia coli strains.

Authors:  M Andraud; C Chauvin; P Sanders; M Laurentie
Journal:  Antimicrob Agents Chemother       Date:  2010-11-15       Impact factor: 5.191

3.  Mutant prevention concentration (MPC) of ciprofloxacin against Salmonella enterica of epidemic and poultry origin.

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Journal:  Curr Microbiol       Date:  2010-09-25       Impact factor: 2.188

4.  Detection of different β-lactamases encoding genes, including blaNDM, and plasmid-mediated quinolone resistance genes in different water sources from Brazil.

Authors:  Danilo Garcia Sanchez; Fernanda Maciel de Melo; Eduardo Angelino Savazzi; Eliana Guedes Stehling
Journal:  Environ Monit Assess       Date:  2018-06-16       Impact factor: 2.513

5.  Early postoperative fluoroquinolone use is associated with an increased revision rate after arthroscopic rotator cuff repair.

Authors:  Jourdan M Cancienne; Stephen F Brockmeier; Scott A Rodeo; Chris Young; Brian C Werner
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2016-10-13       Impact factor: 4.342

Review 6.  Instructive Advances in Chemical Microbiology Inspired by Nature's Diverse Inventory of Molecules.

Authors:  Ke Liu; Robert W Huigens
Journal:  ACS Infect Dis       Date:  2020-01-06       Impact factor: 5.084

7.  Efficacy and safety of besifloxacin ophthalmic suspension 0.6% in children and adolescents with bacterial conjunctivitis: a post hoc, subgroup analysis of three randomized, double-masked, parallel-group, multicenter clinical trials.

Authors:  Timothy L Comstock; Michael R Paterno; Dale W Usner; Michael E Pichichero
Journal:  Paediatr Drugs       Date:  2010-04-01       Impact factor: 3.022

8.  Epidemiologic relationship between fluoroquinolone-resistant Salmonella enterica Serovar Choleraesuis strains isolated from humans and pigs in Taiwan (1997 to 2002).

Authors:  Chao-Chin Chang; Yi-Hsuan Lin; Chao-Fu Chang; Kuang-Sheng Yeh; Cheng-Hsun Chiu; Chishih Chu; Maw-Sheng Chien; Yuan-Man Hsu; Li-Shu Tsai; Chien-Shun Chiou
Journal:  J Clin Microbiol       Date:  2005-06       Impact factor: 5.948

9.  Clinical evaluation of commercial PCR assays for antimicrobal resistance in Mycoplasma genitalium and estimation of resistance-mediated mutation prevalence in Moscow and Moscow region.

Authors:  Elizaveta Dmitrievna Shedko; Guzel Anvarovna Khayrullina; Elena Nikolaevna Goloveshkina; Vasiliy Gennadevich Akimkin
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2021-01-30       Impact factor: 3.267

10.  Impact of antibiotic resistance in the management of ocular infections: the role of current and future antibiotics.

Authors:  Joseph S Bertino
Journal:  Clin Ophthalmol       Date:  2009-09-24
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