Literature DB >> 15027848

7-Alkoxy-4-phenylamino-3-quinolinecar-bonitriles as dual inhibitors of Src and Abl kinases.

Diane H Boschelli1, Yanong D Wang, Steve Johnson, Biqi Wu, Fei Ye, Ana Carolina Barrios Sosa, Jennifer M Golas, Frank Boschelli.   

Abstract

We previously reported that several 7-alkoxy-4-phenylamino-3-quinolinecarbonitriles were potent inhibitors of Src kinase activity. We disclose here a new highly efficient and versatile route to these compounds, which are also potent inhibitors of Abl kinase.

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Year:  2004        PMID： 15027848     DOI： 10.1021/jm0499458

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


  5 in total

1.  Localized activation of Src-family protein kinases in the mouse egg.

Authors:  Lynda K McGinnis; David F Albertini; William H Kinsey
Journal:  Dev Biol       Date:  2007-03-24       Impact factor: 3.582

2.  Discriminating of ATP competitive Src kinase inhibitors and decoys using self-organizing map and support vector machine.

Authors:  Aixia Yan; Xiaoying Hu; Kai Wang; Jing Sun
Journal:  Mol Divers       Date:  2012-11-02       Impact factor: 2.943

3.  Functions of Fyn kinase in the completion of meiosis in mouse oocytes.

Authors:  Lynda K McGinnis; William H Kinsey; David F Albertini
Journal:  Dev Biol       Date:  2008-12-11       Impact factor: 3.582

4.  Melanoma Differentiation-associated Gene 7/IL-24 Exerts Cytotoxic Effects by Altering the Alternative Splicing of Bcl-x Pre-mRNA via the SRC/PKCδ Signaling Axis.

Authors:  Brian A Shapiro; Ngoc T Vu; Michael D Shultz; Jacqueline C Shultz; Jennifer A Mietla; Mazen M Gouda; Adly Yacoub; Paul Dent; Paul B Fisher; Margaret A Park; Charles E Chalfant
Journal:  J Biol Chem       Date:  2016-08-12       Impact factor: 5.157

5.  Regulation of Fibroblast Cell Polarity by Src Tyrosine Kinase.

Authors:  Kazuo Katoh
Journal:  Biomedicines       Date:  2021-02-01
  5 in total

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