BACKGROUND: We studied serum/Plasma iron, ferritin, transferrin concentrations, and total iron binding capacity (TIBC) in addition to highly sensitive C-reactive protein (hs-CRP), low-density lipoprotein (LDL) cholesterol and magnesium concentrations in a population of 800 in- and outpatients and defined new 95% reference intervals for pediatrics using the Dade Behring RxL Dimension Clinical Chemistry System. METHODS: Plasma/serum concentrations of the above analytes were determined on patient samples accrued from January to June 2003 and the data were analyzed employing a computer adapted Hoffmann approach. RESULTS AND CONCLUSIONS: New pediatric reference intervals on the Dade RxL Dimension were obtained for serum iron, ferritin, transferrin, TIBC, hs-CRP, LDL-cholesterol and magnesium. This work represents the first hs-CRP data for children <3 years old. The values for all the analytes were established on new data (n=800). These values are new for hs-CRP and LDL cholesterol, while for iron, ferritin and magnesium these intervals are more reliable than those previously published by our group which had used regression equations on samples measured by the old (Vitros/Immuno1) methods for which intervals were available.
BACKGROUND: We studied serum/Plasma iron, ferritin, transferrin concentrations, and total iron binding capacity (TIBC) in addition to highly sensitive C-reactive protein (hs-CRP), low-density lipoprotein (LDL) cholesterol and magnesium concentrations in a population of 800 in- and outpatients and defined new 95% reference intervals for pediatrics using the Dade Behring RxL Dimension Clinical Chemistry System. METHODS: Plasma/serum concentrations of the above analytes were determined on patient samples accrued from January to June 2003 and the data were analyzed employing a computer adapted Hoffmann approach. RESULTS AND CONCLUSIONS: New pediatric reference intervals on the Dade RxL Dimension were obtained for serum iron, ferritin, transferrin, TIBC, hs-CRP, LDL-cholesterol and magnesium. This work represents the first hs-CRP data for children <3 years old. The values for all the analytes were established on new data (n=800). These values are new for hs-CRP and LDL cholesterol, while for iron, ferritin and magnesium these intervals are more reliable than those previously published by our group which had used regression equations on samples measured by the old (Vitros/Immuno1) methods for which intervals were available.
Authors: R Gottschalk; R Wigand; C F Dietrich; G Oremek; F Liebisch; D Hoelzer; J P Kaltwasser Journal: Clin Chim Acta Date: 2000-03 Impact factor: 3.786
Authors: H Schlenz; T Intemann; M Wolters; E M González-Gil; A Nappo; A Fraterman; T Veidebaum; D Molnar; M Tornaritis; I Sioen; S Mårild; L Iacoviello; W Ahrens Journal: Int J Obes (Lond) Date: 2014-09 Impact factor: 5.095