Literature DB >> 15025150

The utility of ketoprofen for alleviating pain following dehorning in young dairy calves.

Barry N Milligan1, Todd Duffield, Kerry Lissemore.   

Abstract

To determine if ketoprofen, in addition to local anaesthesia, reduces pain following dehorning, we experimentally dehorned dairy calves, less than 2 weeks of age, with (20 calves) or without (20 calves) intramuscular injections of ketoprofen. All calves received a local anesthetic (lidocaine) prior to dehorning and were dehorned with heat cauterization. Cortisol concentration was measured via jugular blood samples taken immediately before dehorning and at 3 and 6 hours following dehorning. Calf behavior was recorded between 0 and 2, 3 and 5, and 6 and 8 hours following dehorning. There was no significant (P > 0.10) effect on creep feed consumption, cortisol concentration, or any of the behavioral measures during the time periods studied. However, the difference in cortisol concentrations from the time of dehorning until 3 hours later was significantly lower (P < 0.05) in the ketoprofen-treated group. These results suggest that ketoprofen, in addition to local anesthesia, may alleviate short-term pain following dehorning with a butane dehorning device in dairy calves less than 2 weeks of age.

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Year:  2004        PMID: 15025150      PMCID: PMC548603     

Source DB:  PubMed          Journal:  Can Vet J        ISSN: 0008-5286            Impact factor:   1.008


  13 in total

1.  Effect of local anaesthetic combined with wound cauterisation on the cortisol response to dehorning in calves.

Authors:  M A Sutherland; D J Mellor; K J Stafford; N G Gregory; R A Bruce; R N Ward
Journal:  Aust Vet J       Date:  2002-03       Impact factor: 1.281

2.  A comparison of catecholamine and cortisol responses of young lambs and calves to painful husbandry procedures.

Authors:  D J Mellor; K J Stafford; S E Todd; T E Lowe; N G Gregory; R A Bruce; R N Ward
Journal:  Aust Vet J       Date:  2002-04       Impact factor: 1.281

3.  Effects of local anaesthesia of 4 to 8 hours' duration on the acute cortisol response to scoop dehorning in calves.

Authors:  C M McMeekan; D J Mellor; K J Stafford; R A Bruce; R N Ward; N G Gregory
Journal:  Aust Vet J       Date:  1998-04       Impact factor: 1.281

4.  Acute cortisol responses of calves to scoop dehorning using local anaesthesia and/or cautery of the wound.

Authors:  S P Sylvester; D J Mellor; K J Stafford; R A Bruce; R N Ward
Journal:  Aust Vet J       Date:  1998-02       Impact factor: 1.281

5.  Behavioural, endocrine and cardiac responses in young calves undergoing dehorning without and with use of sedation and analgesia.

Authors:  C Grondahl-Nielsen; H B Simonsen; J D Lund; M Hesselholt
Journal:  Vet J       Date:  1999-07       Impact factor: 2.688

6.  Reducing pain after dehorning in dairy calves.

Authors:  P M Faulkner; D M Weary
Journal:  J Dairy Sci       Date:  2000-09       Impact factor: 4.034

7.  Cortisol responses of calves to two methods of disbudding used with or without local anaesthetic.

Authors:  N J Petrie; D J Mellor; K J Stafford; R A Bruce; R N Ward
Journal:  N Z Vet J       Date:  1996-02       Impact factor: 1.628

8.  Cortisol responses to dehorning of calves given a 5-h local anaesthetic regimen plus phenylbutazone, ketoprofen, or adrenocorticotropic hormone prior to dehorning.

Authors:  M A Sutherland; D J Mellor; K J Stafford; N G Gregory; R A Bruce; R N Ward
Journal:  Res Vet Sci       Date:  2002-10       Impact factor: 2.534

9.  Pharmacokinetics and pharmacodynamics of ketoprofen in calves applying PK/PD modelling.

Authors:  M F Landoni; F M Cunningham; P Lees
Journal:  J Vet Pharmacol Ther       Date:  1995-10       Impact factor: 1.786

10.  Pharmacokinetics and pharmacodynamics of ketoprofen enantiomers in calves.

Authors:  M F Landoni; P Lees
Journal:  Chirality       Date:  1995       Impact factor: 2.437

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  5 in total

1.  Reduction in pain response by combined use of local lidocaine anesthesia and systemic ketoprofen in dairy calves dehorned by heat cauterization.

Authors:  Todd F Duffield; Anneliese Heinrich; Suzanne T Millman; Andrew DeHaan; Shelley James; Kerry Lissemore
Journal:  Can Vet J       Date:  2010-03       Impact factor: 1.008

Review 2.  Welfare Effects of the Use of a Combination of Local Anesthesia and NSAID for Disbudding Analgesia in Dairy Calves-Reviewed Across Different Welfare Concerns.

Authors:  Mette S Herskin; Bodil H Nielsen
Journal:  Front Vet Sci       Date:  2018-06-05

3.  Scientific report on the effects of farming systems on dairy cow welfare and disease.

Authors: 
Journal:  EFSA J       Date:  2009-07-09

4.  Behavioral and Physiological Response to Routine Thermal Disbudding in Dairy Calves Treated with Transdermal Flunixin Meglumine.

Authors:  Tara Gaab; Mary Wright; Meghann Pierdon
Journal:  Animals (Basel)       Date:  2022-02-22       Impact factor: 2.752

5.  Indication of social buffering in disbudded calves.

Authors:  Katarína Bučková; Ágnes Moravcsíková; Radka Šárová; Radko Rajmon; Marek Špinka
Journal:  Sci Rep       Date:  2022-08-03       Impact factor: 4.996

  5 in total

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