Literature DB >> 15024383

A receptor for green tea polyphenol EGCG.

Hirofumi Tachibana1, Kiyoshi Koga, Yoshinori Fujimura, Koji Yamada.   

Abstract

The major polyphenol in green tea, (-)-epigallocatechin-3-gallate (EGCG), has been shown to prevent carcinogenesis. We have identified a receptor that mediates the anticancer activity of EGCG. Expression of the metastasis-associated 67-kDa laminin receptor confers EGCG responsiveness to cancer cells at physiologically relevant concentrations. Experiments using surface plasmon resonance demonstrate binding of EGCG to the 67-kDa laminin receptor with a nanomolar K (d) value.

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Year:  2004        PMID： 15024383     DOI： 10.1038/nsmb743

Source DB:  PubMed          Journal:  Nat Struct Mol Biol        ISSN： 1545-9985            Impact factor:   15.369


  153 in total

1.  Epigallocatechin-3-gallate (EGCG) protects against chromate-induced toxicity in vitro.

Authors:  Fen Wu; Hong Sun; Thomas Kluz; Hailey A Clancy; Kathrin Kiok; Max Costa
Journal:  Toxicol Appl Pharmacol       Date:  2011-11-04       Impact factor: 4.219

2.  Epigallocatechin-3-gallate regulates cell growth, cell cycle and phosphorylated nuclear factor-κB in human dermal fibroblasts.

Authors:  Dong-wook Han; Mi Hee Lee; Hak Hee Kim; Suong-hyu Hyon; Jong-chul Park
Journal:  Acta Pharmacol Sin       Date:  2011-04-25       Impact factor: 6.150

3.  Biological actions of green tea catechins on cardiac troponin C.

Authors:  Naoto Tadano; Cheng-Kun Du; Fumiaki Yumoto; Sachio Morimoto; Mika Ohta; Ming-Fang Xie; Koji Nagata; Dong-Yun Zhan; Qun-Wei Lu; Yoshikazu Miwa; Fumi Takahashi-Yanaga; Masaru Tanokura; Iwao Ohtsuki; Toshiyuki Sasaguri
Journal:  Br J Pharmacol       Date:  2010-11       Impact factor: 8.739

Review 4.  Structure-guided identification of a laminin binding site on the laminin receptor precursor.

Authors:  Kelly V Jamieson; Stevan R Hubbard; Daniel Meruelo
Journal:  J Mol Biol       Date:  2010-10-30       Impact factor: 5.469

5.  Exploring the chemical sensitivity of a carbon nanotube/green tea composite.

Authors:  Yanan Chen; Yang Doo Lee; Harindra Vedala; Brett L Allen; Alexander Star
Journal:  ACS Nano       Date:  2010-11-02       Impact factor: 15.881

6.  Green Tea Polyphenol Epigallocatechin-3-gallate Suppresses Toll-like Receptor 4 Expression via Up-regulation of E3 Ubiquitin-protein Ligase RNF216.

Authors:  Motofumi Kumazoe; Yuki Nakamura; Mai Yamashita; Takashi Suzuki; Kanako Takamatsu; Yuhui Huang; Jaehoon Bae; Shuya Yamashita; Motoki Murata; Shuhei Yamada; Yuki Shinoda; Wataru Yamaguchi; Yui Toyoda; Hirofumi Tachibana
Journal:  J Biol Chem       Date:  2017-02-01       Impact factor: 5.157

7.  Green tea polyphenols precondition against cell death induced by oxygen-glucose deprivation via stimulation of laminin receptor, generation of reactive oxygen species, and activation of protein kinase Cε.

Authors:  Usha Gundimeda; Thomas H McNeill; Albert A Elhiani; Jason E Schiffman; David R Hinton; Rayudu Gopalakrishna
Journal:  J Biol Chem       Date:  2012-08-09       Impact factor: 5.157

Review 8.  Cancer preventive mechanisms of the green tea polyphenol (-)-epigallocatechin-3-gallate.

Authors:  Lei Chen; Hong-Yu Zhang
Journal:  Molecules       Date:  2007-05-03       Impact factor: 4.411

Review 9.  Signal transduction and molecular targets of selected flavonoids.

Authors:  Ann M Bode; Zigang Dong
Journal:  Antioxid Redox Signal       Date:  2013-04-15       Impact factor: 8.401

Review 10.  Mechanisms of body weight reduction and metabolic syndrome alleviation by tea.

Authors:  Chung S Yang; Jinsong Zhang; Le Zhang; Jinbao Huang; Yijun Wang
Journal:  Mol Nutr Food Res       Date:  2015-12-09       Impact factor: 5.914
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