Literature DB >> 15022174

Effect of green tea polyphenols on the genes with atherosclerotic potential.

D Kaul1, K Sikand, A R Shukla.   

Abstract

The genomics of atherosclerosis can arise as a result of cross-talk between the genes coding for the LDL-receptor (LDL-R), LXR-alpha, PPARs (alpha, gamma), CD36 and C-myc because these genes control lipid metabolism, cytokine production and cellular activity within the arterial wall. The effect of green tea polyphenols (GTPs) upon such genomics revealed their ability to down-regulate genes coding for PPAR-gamma, CD36, LXR-alpha, C-myc coupled with up-regulation of genes coding for LDL-R and PPAR-alpha at the transcriptional level. Based upon these results, it is proposed that GTPs have the inherent capacity to inhibit the development of atherosclerotic lesions. Copyright 2004 John Wiley & Sons, Ltd.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 15022174     DOI： 10.1002/ptr.1411

Source DB:  PubMed          Journal:  Phytother Res        ISSN： 0951-418X            Impact factor:   5.878


  7 in total

1.  Functional genomics of PPAR-gamma in human immunomodulatory cells.

Authors:  Deepak Kaul; Paras K Anand; Amit Khanna
Journal:  Mol Cell Biochem       Date:  2006-04-22       Impact factor: 3.396

2.  Importance of LXR-alpha transcriptome in the modulation of innate immunity.

Authors:  Deepak Kaul; Ankur Gautam; Kavleen Sikand
Journal:  Mol Cell Biochem       Date:  2006-06-07       Impact factor: 3.396

3.  Modulation of PI3K-LXRα-dependent lipogenesis mediated by oxidative/nitrosative stress contributes to inhibition of HCV replication by quercetin.

Authors:  Sandra Pisonero-Vaquero; María V García-Mediavilla; Francisco Jorquera; Pedro L Majano; Marta Benet; Ramiro Jover; Javier González-Gallego; Sonia Sánchez-Campos
Journal:  Lab Invest       Date:  2014-02-03       Impact factor: 5.662

Review 4.  The anti-obesity effects of green tea in human intervention and basic molecular studies.

Authors:  J Huang; Y Wang; Z Xie; Y Zhou; Y Zhang; X Wan
Journal:  Eur J Clin Nutr       Date:  2014-07-30       Impact factor: 4.016

5.  Dietary green tea extract lowers plasma and hepatic triglycerides and decreases the expression of sterol regulatory element-binding protein-1c mRNA and its responsive genes in fructose-fed, ovariectomized rats.

Authors:  Sudeep Shrestha; Sarah J Ehlers; Ji-Young Lee; Maria-Luz Fernandez; Sung I Koo
Journal:  J Nutr       Date:  2009-02-04       Impact factor: 4.798

Review 6.  Molecular targets of dietary polyphenols with anti-inflammatory properties.

Authors:  Joo-Heon Yoon; Seung Joon Baek
Journal:  Yonsei Med J       Date:  2005-10-31       Impact factor: 2.759

7.  Dietary flavanols modulate the transcription of genes associated with cardiovascular pathology without changes in their DNA methylation state.

Authors:  Dragan Milenkovic; Wim Vanden Berghe; Céline Boby; Christine Leroux; Ken Declerck; Katarzyna Szarc vel Szic; Karen Heyninck; Kris Laukens; Martin Bizet; Matthieu Defrance; Sarah Dedeurwaerder; Emilie Calonne; Francois Fuks; Guy Haegeman; Guido R M M Haenen; Aalt Bast; Antje R Weseler
Journal:  PLoS One       Date:  2014-04-24       Impact factor: 3.240
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.