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Literature DB >> 15021898

Epstein-Barr virus oncogenesis and the ubiquitin-proteasome system.

Abstract

Epstein-Barr virus (EBV), a human herpesvirus associated with lymphoid and epithelial cell tumors, encodes several proteins that exploit the ubiquitin-proteasome system to regulate latency and allow the persistence of infected cells in immunocompetent hosts. Further modifications of ubiquitin-dependent proteolysis by activated cellular oncogenes contribute to malignant transformation. A detailed understanding of these processes may lead to the development of new therapeutic strategies for EBV-associated cancers.

Entities: Disease Species

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Year: 2004 PMID： 15021898 DOI： 10.1038/sj.onc.1207372

Source DB: PubMed Journal: Oncogene ISSN： 0950-9232 Impact factor: 9.867

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Cited

20 in total

Review 1. DRiPs solidify: progress in understanding endogenous MHC class I antigen processing.

Authors: Jonathan W Yewdell
Journal: Trends Immunol Date: 2011-09-29 Impact factor: 16.687

Review 2. MHC class I antigen presentation: learning from viral evasion strategies.

Authors: Ted H Hansen; Marlene Bouvier
Journal: Nat Rev Immunol Date: 2009-07 Impact factor: 53.106

3. Epstein-Barr virus in human malignancy: a special reference to Epstein-Barr virus associated gastric carcinoma.

Authors: Mee Soo Chang; Woo Ho Kim
Journal: Cancer Res Treat Date: 2005-10-31 Impact factor: 4.679

4. Characterization of an human leucocyte antigen A2-restricted Epstein-Barr virus nuclear antigen-1-derived cytotoxic T-lymphocyte epitope.

Authors: Diego Marescotti; Federica Destro; Anna Baldisserotto; Mauro Marastoni; Giuseppe Coppotelli; Maria Masucci; Riccardo Gavioli
Journal: Immunology Date: 2009-11-16 Impact factor: 7.397

5. Development of drugs for Epstein-Barr virus using high-throughput in silico virtual screening.

Authors: Ning Li; Scott Thompson; Hualiang Jiang; Paul M Lieberman; Cheng Luo
Journal: Expert Opin Drug Discov Date: 2010-12 Impact factor: 6.098

6. The Linear Ubiquitin Assembly Complex Modulates Latent Membrane Protein 1 Activation of NF-κB and Interferon Regulatory Factor 7.

Authors: Ling Wang; Yujia Wang; Juan Zhao; Junping Ren; Kenton H Hall; Jonathan P Moorman; Zhi Q Yao; Shunbin Ning
Journal: J Virol Date: 2017-01-31 Impact factor: 5.103

Epstein-Barr virus oncogenesis and the ubiquitin-proteasome system.

Review 1. DRiPs solidify: progress in understanding endogenous MHC class I antigen processing.

Review 2. MHC class I antigen presentation: learning from viral evasion strategies.

3. Epstein-Barr virus in human malignancy: a special reference to Epstein-Barr virus associated gastric carcinoma.

4. Characterization of an human leucocyte antigen A2-restricted Epstein-Barr virus nuclear antigen-1-derived cytotoxic T-lymphocyte epitope.

5. Development of drugs for Epstein-Barr virus using high-throughput in silico virtual screening.

6. The Linear Ubiquitin Assembly Complex Modulates Latent Membrane Protein 1 Activation of NF-κB and Interferon Regulatory Factor 7.

7. Proteasome inhibition attenuates coxsackievirus-induced myocardial damage in mice.

8. Epstein-barr virus encodes three bona fide ubiquitin-specific proteases.

9. Gene bi-targeting by viral and human miRNAs.

10. Commentary: mechanistic considerations for associations between formaldehyde exposure and nasopharyngeal carcinoma.