Literature DB >> 15020780

Design, construction, and use of tissue microarrays.

Stephen M Hewitt1.   

Abstract

Tissue microarrays are a platform for high-throughput analysis of tissue specimens in research. They are used for target verification of results from complementary deoxyribonucleic acid (cDNA) microarrays, expression profiling of tumors and tissues, as well as in epidemiology-based investigations. Tissue microarrays are a simple reagent that can be constructed from archival paraffin-embedded tissue for immunohistochemical staining, in situ hybridization, and other methodologies. The design and precision in execution of a tissue microarray is essential to obtain the desired results. Tissue microarrays are a powerful proteomic platform for research.

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Year:  2004        PMID： 15020780     DOI： 10.1385/1-59259-759-9:061

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  16 in total

1.  Analysis of protein expression in cell microarrays: a tool for antibody-based proteomics.

Authors:  Ann-Catrin Andersson; Sara Strömberg; Helena Bäckvall; Caroline Kampf; Mathias Uhlen; Kenneth Wester; Fredrik Pontén
Journal:  J Histochem Cytochem       Date:  2006-09-06       Impact factor: 2.479

2.  Evaluation of eIF4E expression in an osteosarcoma-specific tissue microarray.

Authors:  Tanasa S Osborne; Ling Ren; John H Healey; Lauren Q Shapiro; Alexander J Chou; Richard G Gorlick; Stephen M Hewitt; Chand Khanna
Journal:  J Pediatr Hematol Oncol       Date:  2011-10       Impact factor: 1.289

3.  A 'waterfall' transfer-based workflow for improved quality of tissue microarray construction and processing in breast cancer research.

Authors:  M Oberländer; H Alkemade; S Bünger; F Ernst; C Thorns; T Braunschweig; J K Habermann
Journal:  Pathol Oncol Res       Date:  2014-03-07       Impact factor: 3.201

4.  Expression of the cytoskeleton linker protein ezrin in human cancers.

Authors:  Benjamin Bruce; Gaurav Khanna; Ling Ren; Goran Landberg; Karin Jirström; Charles Powell; Alain Borczuk; Evan T Keller; Kirk J Wojno; Paul Meltzer; Kristin Baird; Andrea McClatchey; Anthony Bretscher; Stephen M Hewitt; Chand Khanna
Journal:  Clin Exp Metastasis       Date:  2007-03-17       Impact factor: 5.150

5.  Ezrin mediates growth and survival in Ewing's sarcoma through the AKT/mTOR, but not the MAPK, signaling pathway.

Authors:  Kartik Krishnan; Ben Bruce; Stephen Hewitt; Dafydd Thomas; Chand Khanna; Lee J Helman
Journal:  Clin Exp Metastasis       Date:  2006-09-22       Impact factor: 5.150

6.  Expression of lysosome-associated protein transmembrane 4B-35 in cancer and its correlation with the differentiation status of hepatocellular carcinoma.

Authors:  Cong Peng; Rou-Li Zhou; Gen-Ze Shao; Jing-An Rui; Shao-Bin Wang; Ming Lin; Sha Zhang; Zi-Feng Gao
Journal:  World J Gastroenterol       Date:  2005-05-14       Impact factor: 5.742

7.  Clinical and therapeutic implications of Sprouty2 feedback dysregulation in BRAF V600E-mutation-positive papillary thyroid cancer.

Authors:  Linda A Dultz; Shumon Dhar; Jennifer B Ogilvie; Keith S Heller; Dafna Bar-Sagi; Kepal N Patel
Journal:  Surgery       Date:  2013-10-02       Impact factor: 3.982

8.  4-HNE Immunohistochemistry and Image Analysis for Detection of Lipid Peroxidation in Human Liver Samples Using Vitamin E Treatment in NAFLD as a Proof of Concept.

Authors:  Maren C Podszun; Joon-Yong Chung; Kris Ylaya; David E Kleiner; Stephen M Hewitt; Yaron Rotman
Journal:  J Histochem Cytochem       Date:  2020-09       Impact factor: 2.479

Review 9.  Multiplex quantitative measurement of mRNAs from fixed tissue microarray sections.

Authors:  Michael Armani; Michael Tangrea; Brian Yang; Alex Rosenberg; Kris Ylaya; Jennifer Morris; Jaime Rodriguez-Canales; Jeffrey Hanson; Benjamin Shapiro; Michael R Emmert-Buck; Elisabeth Smela; Stephen M Hewitt
Journal:  Appl Immunohistochem Mol Morphol       Date:  2014 May-Jun

Review 10.  Tissue microarrays as a tool in the discovery and validation of tumor markers.

Authors:  Stephen M Hewitt
Journal:  Methods Mol Biol       Date:  2009
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