Literature DB >> 15020289

Clinical significance of breakthrough fungemia caused by azole-resistant Candida tropicalis in patients with hematologic malignancies.

Yoshinari Myoken, Tai-ichi Kyo, Megumu Fujihara, Tatsumi Sugata, Yuzuru Mikami.   

Abstract

A 5-year retrospective analysis of fungemia in patients with hematologic malignancies revealed that four patients, who received fluconazole and itraconazole during neutropenia, developed breakthrough candidemia due to azole-resistant Candida tropicalis isolates. This observation suggests that causative organisms of candidemia in neutropenic patients receiving azoles should be suspected of being azole-resistant.

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Year:  2004        PMID: 15020289

Source DB:  PubMed          Journal:  Haematologica        ISSN: 0390-6078            Impact factor:   9.941


  9 in total

1.  Identification of Azole Resistance Markers in Clinical Isolates of Candida tropicalis Using cDNA-AFLP Method.

Authors:  Ali Kanani; Farideh Zaini; Parivash Kordbacheh; Mehraban Falahati; Sassan Rezaie; Roshanak Daie; Shirin Farahyar; Mahin Safara; Roohollah Fateh; Ebrahim Faghihloo; Azam Fattahi; Mansour Heidari
Journal:  J Clin Lab Anal       Date:  2015-04-14       Impact factor: 2.352

2.  Mechanisms of azole resistance in a clinical isolate of Candida tropicalis.

Authors:  Patrick Vandeputte; Gérald Larcher; Thierry Bergès; Gilles Renier; Dominique Chabasse; Jean-Philippe Bouchara
Journal:  Antimicrob Agents Chemother       Date:  2005-11       Impact factor: 5.191

3.  Candida tropicalis as a Predominant Isolate from Clinical Specimens and its Antifungal Susceptibility Pattern in a Tertiary Care Hospital in Southern India.

Authors:  Binesh Lal Yesudhason; Kalyani Mohanram
Journal:  J Clin Diagn Res       Date:  2015-07-01

4.  In vitro susceptibility of breakthrough Candida bloodstream isolates correlates with daily and cumulative doses of fluconazole.

Authors:  Cornelius J Clancy; Benjamin Staley; M Hong Nguyen
Journal:  Antimicrob Agents Chemother       Date:  2006-10       Impact factor: 5.191

5.  Multilocus sequence typing of Candida tropicalis shows the presence of different clonal clusters and fluconazole susceptibility profiles in sequential isolates from candidemia patients in Sao Paulo, Brazil.

Authors:  Marcello Mihailenko Chaves Magri; Michele Soares Gomes-Gouvêa; Vera Lúcia Teixeira de Freitas; Adriana Lopes Motta; Maria Luiza Moretti; Maria Aparecida Shikanai-Yasuda
Journal:  J Clin Microbiol       Date:  2012-11-14       Impact factor: 5.948

6.  Use of Fungal Diagnostics and Therapy in Pediatric Cancer Patients in Resource-Limited Settings.

Authors:  Sheena Mukkada; Jeannette Kirby; Nopporn Apiwattanakul; Randall T Hayden; Miguela A Caniza
Journal:  Curr Clin Microbiol Rep       Date:  2016-04-18

7.  Candida tropicalis antifungal cross-resistance is related to different azole target (Erg11p) modifications.

Authors:  A Forastiero; A C Mesa-Arango; A Alastruey-Izquierdo; L Alcazar-Fuoli; L Bernal-Martinez; T Pelaez; J F Lopez; J O Grimalt; A Gomez-Lopez; I Cuesta; O Zaragoza; E Mellado
Journal:  Antimicrob Agents Chemother       Date:  2013-07-22       Impact factor: 5.191

8.  Candidaemia in patients with haematological disorders and stem cell transplant.

Authors:  Ka Al-Anazi; Am Al-Jasser
Journal:  Libyan J Med       Date:  2006-11-21       Impact factor: 1.657

9.  Risk factors and clinical outcomes of breakthrough yeast bloodstream infections in patients with hematological malignancies in the era of newer antifungal agents.

Authors:  Si-Hyun Kim; Jae-Ki Choi; Sung-Yeon Cho; Hyo-Jin Lee; Sun Hee Park; Su-Mi Choi; Dong-Gun Lee; Jung-Hyun Choi; Jin-Hong Yoo; Jong-Wook Lee
Journal:  Med Mycol       Date:  2018-02-01       Impact factor: 4.076

  9 in total

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