Literature DB >> 15019341

Orthokeratology lens-related corneal ulcers in children: a case series.

Alvin L Young1, Alfred T S Leung, Lulu L Cheng, Ricky W K Law, Angus K K Wong, Dennis S C Lam.   

Abstract

OBJECTIVE: Orthokeratology is a process by which the corneal curvature is flattened by sequentially fitting rigid gas permeable contact lenses of decreasing central curvature. There has been a resurgence of interest with the recent introduction of reverse geometry lenses. Although promising results have been described in reducing the myopic refractive error, the use of these lenses can be associated with corneal problems, as reported in this case series.
DESIGN: Observational case series. PARTICIPANTS: Six children with orthokeratology-related corneal ulcers.
METHODS: Consecutive cases of orthokeratology lens (OKL)-related corneal ulcers in children presented to a tertiary referral center (March 1999-June 2001) were reviewed. MAIN OUTCOME MEASURES: Preinfection and postinfection visual acuity, refraction, any organisms identified.
RESULTS: Six children between the ages of 9 and 14 years (mean = 12.1) were treated. The male:female ratio was 1:5. All cases were unilateral, with equal numbers of left and right eyes. All children wore the OKL at night for a duration of 8 to 12 hours, with the onset of infection between 3 and 36 months (mean = 16.6) of OKL wear. All of the patients suffered a resultant best-corrected visual acuity loss. Five of the 6 cases were culture positive for Pseudomonas aeruginosa.
CONCLUSIONS: In view of the temporary benefits of orthokeratology, together with a known increased risk of infection associated with overnight lens wear, parents of children considering orthokeratology must be informed and warned of the potential for permanent loss of vision. The ophthalmic community should have a heightened awareness of the associated complications.

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Year:  2004        PMID: 15019341     DOI: 10.1016/j.ophtha.2003.06.003

Source DB:  PubMed          Journal:  Ophthalmology        ISSN: 0161-6420            Impact factor:   12.079


  11 in total

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Authors:  Nurul Huda Khan; Yoshikazu Ishii; Noriko Kimata-Kino; Hidetake Esaki; Tomohiko Nishino; Masahiko Nishimura; Kazuhiro Kogure
Journal:  Microb Ecol       Date:  2007-02       Impact factor: 4.552

Review 2.  The persistent dilemma of microbial keratitis: Global burden, diagnosis, and antimicrobial resistance.

Authors:  Lawson Ung; Paulo J M Bispo; Swapna S Shanbhag; Michael S Gilmore; James Chodosh
Journal:  Surv Ophthalmol       Date:  2018-12-24       Impact factor: 6.048

3.  A prospective interventional study of effect of accelerated orthokeratology on the corneal curvature and refraction among young adults with myopia.

Authors:  M A Khan; Ashutosh Gupta; T S Ahluwalia; P S Moulick; V S Gurunadh; Sandeep Gupta
Journal:  Med J Armed Forces India       Date:  2016-04-16

4.  Molecular characterization of Acanthamoeba isolated from amebic keratitis related to orthokeratology lens overnight wear.

Authors:  Sun Joo Lee; Hae Jin Jeong; Ji Eun Lee; Jong Soo Lee; Ying Hua Xuan; Hyun-Hee Kong; Dong-Il Chung; Mee-Sun Ock; Hak Sun Yu
Journal:  Korean J Parasitol       Date:  2006-12       Impact factor: 1.341

Review 5.  Infectious keratitis and orthokeratology lens use: a systematic review.

Authors:  Ka Wai Kam; Wing Yung; Gabriel Ka Hin Li; Li Jia Chen; Alvin L Young
Journal:  Infection       Date:  2017-05-22       Impact factor: 3.553

Review 6.  Microbial contamination of contact lenses, lens care solutions, and their accessories: a literature review.

Authors:  Loretta B Szczotka-Flynn; Eric Pearlman; Mahmoud Ghannoum
Journal:  Eye Contact Lens       Date:  2010-03       Impact factor: 2.018

7.  Multilocus sequence typing and phylogenetic analyses of Pseudomonas aeruginosa Isolates from the ocean.

Authors:  Nurul Huda Khan; Mahbuba Ahsan; Susumu Yoshizawa; Shoichi Hosoya; Akira Yokota; Kazuhiro Kogure
Journal:  Appl Environ Microbiol       Date:  2008-08-29       Impact factor: 4.792

8.  Acanthamoeba keratitis related to orthokeratology.

Authors:  Ji-Eun Lee; Tae Won Hahn; Boo Sup Oum; Hee Young Choi; Hak Sun Yu; Jong Soo Lee
Journal:  Int Ophthalmol       Date:  2007-03-22       Impact factor: 2.029

9.  Microbial Keratitis Profile at a University Hospital in Hong Kong.

Authors:  Tracy H T Lai; Vishal Jhanji; Alvin L Young
Journal:  Int Sch Res Notices       Date:  2014-11-11

10.  Clinical and microbiological profile of infectious keratitis in children.

Authors:  Patricia Chirinos-Saldaña; Victor Manuel Bautista de Lucio; Julio Cesar Hernandez-Camarena; Alejandro Navas; Arturo Ramirez-Miranda; Lizet Vizuet-Garcia; Mariana Ortiz-Casas; Nadia Lopez-Espinosa; Carolina Gaona-Juarez; Luis Antonio Bautista-Hernandez; Enrique O Graue-Hernandez
Journal:  BMC Ophthalmol       Date:  2013-10-16       Impact factor: 2.209

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