Literature DB >> 15019267

Is ethanol a pro-drug? The role of acetaldehyde in the central effects of ethanol.

Etienne Quertemont1, Sophie Tambour.   

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Year:  2004        PMID： 15019267     DOI： 10.1016/j.tips.2004.01.001

Source DB:  PubMed          Journal:  Trends Pharmacol Sci        ISSN： 0165-6147            Impact factor:   14.819


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  14 in total

1.  Binge ethanol administration enhances the MDMA-induced long-term 5-HT neurotoxicity in rat brain.

Authors:  María Izco; Laura Orio; Esther O'Shea; M Isabel Colado
Journal:  Psychopharmacology (Berl)       Date:  2006-10-18       Impact factor: 4.530

2.  Ethanol as a prodrug: brain metabolism of ethanol mediates its reinforcing effects.

Authors:  Eduardo Karahanian; María Elena Quintanilla; Lutske Tampier; Mario Rivera-Meza; Diego Bustamante; Víctor Gonzalez-Lira; Paola Morales; Mario Herrera-Marschitz; Yedy Israel
Journal:  Alcohol Clin Exp Res       Date:  2011-02-17       Impact factor: 3.455

3.  Enhancement of camptothecin-induced topoisomerase I cleavage complexes by the acetaldehyde adduct N2-ethyl-2'-deoxyguanosine.

Authors:  Smitha Antony; Jacob A Theruvathu; P J Brooks; Diem-Thu Lesher; Matt Redinbo; Yves Pommier
Journal:  Nucleic Acids Res       Date:  2004-10-21       Impact factor: 16.971

4.  An acetaldehyde-sequestering agent inhibits appetitive reinforcement and behavioral stimulation induced by ethanol in preweanling rats.

Authors:  Ricardo Marcos Pautassi; Michael E Nizhnikov; Ma Carolina Fabio; Norman E Spear
Journal:  Pharmacol Biochem Behav       Date:  2010-10-14       Impact factor: 3.533

5.  High Ethanol and Acetaldehyde Inhibit Glutamatergic Transmission in the Hippocampus of Aldh2-Knockout and C57BL/6N Mice: an In Vivo and Ex Vivo Analysis.

Authors:  Mostofa Jamal; Asuka Ito; Naoko Tanaka; Takanori Miki; Kiyoshi Ameno; Hiroshi Kinoshita
Journal:  Neurotox Res       Date:  2020-02-15       Impact factor: 3.911

6.  The role of acetaldehyde in ethanol reinforcement assessed by Pavlovian conditioning in newborn rats.

Authors:  Samanta M March; Paula Abate; Norman E Spear; Juan Carlos Molina
Journal:  Psychopharmacology (Berl)       Date:  2012-12-01       Impact factor: 4.530

7.  Behavioral characterization of acetaldehyde in C57BL/6J mice: locomotor, hypnotic, anxiolytic and amnesic effects.

Authors:  Etienne Quertemont; Sophie Tambour; Pascale Bernaerts; Sergey M Zimatkin; Ezio Tirelli
Journal:  Psychopharmacology (Berl)       Date:  2004-05-25       Impact factor: 4.530

8.  Ethanol-derived acetaldehyde: pleasure and pain of alcohol mechanism of action.

Authors:  Giulia Muggironi; Giulia R Fois; Marco Diana
Journal:  Front Behav Neurosci       Date:  2013-07-17       Impact factor: 3.558

9.  Acetaldehyde-reinforcing effects: a study on oral self-administration behavior.

Authors:  Alessandra T Peana; Giulia Muggironi; Marco Diana
Journal:  Front Psychiatry       Date:  2010-09-16       Impact factor: 4.157

10.  Comparative Proteomics Analysis Reveals L-Arginine Activates Ethanol Degradation Pathways in HepG2 Cells.

Authors:  Guokai Yan; Retno Lestari; Baisheng Long; Qiwen Fan; Zhichang Wang; Xiaozhen Guo; Jie Yu; Jun Hu; Xingya Yang; Changqing Chen; Lu Liu; Xiuzhi Li; Agung Purnomoadi; Joelal Achmadi; Xianghua Yan
Journal:  Sci Rep       Date:  2016-03-17       Impact factor: 4.379
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