| Literature DB >> 15018921 |
Hemavathi Challa1, Thomas C Bruice.
Abstract
The synthesis of purine nucleosides capable of making the guanidinium linkage is described for the first time starting from the corresponding 2'-deoxynucleosides. The positively charged mixed base DNG oligomer containing guanine was synthesized on solid-phase using CPG as support from 3' to 5' direction using the precursor building block nucleosides.Entities:
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Year: 2004 PMID： 15018921 DOI： 10.1016/j.bmc.2003.12.043
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641