Literature DB >> 15018815

Nasal embryonic LHRH factor (NELF) expression within the CNS and PNS of the rodent.

P R Kramer1, S Wray.   

Abstract

A novel protein (NELF) was identified screening embryonic luteinizing hormone releasing hormone (LHRH) neurons at different migrational states. Experiments in vitro revealed that NELF functions in olfactory axon outgrowth and subsequently alters LHRH neuronal migration. NELF was not restricted to LHRH neurons in the developing rodent. Multiple CNS and PNS tissues expressed this gene. To characterize the specific regions that express NELF in situ hybridization histochemistry was performed. Within the CNS, cells in the cortex, hippocampus, thalamus and olfactory regions express NELF pre- and postnatally.

Entities:  

Year:  2001        PMID： 15018815     DOI： 10.1016/s1567-133x(01)00004-7

Source DB:  PubMed          Journal:  Brain Res Gene Expr Patterns


  15 in total

Review 1.  From nose to brain: development of gonadotrophin-releasing hormone-1 neurones.

Authors:  S Wray
Journal:  J Neuroendocrinol       Date:  2010-07       Impact factor: 3.627

2.  A role for FE65 in controlling GnRH-1 neurogenesis.

Authors:  Paolo E Forni; Michele Fornaro; Suzanne Guénette; Susan Wray
Journal:  J Neurosci       Date:  2011-01-12       Impact factor: 6.167

3.  NELF is a nuclear protein involved in hypothalamic GnRH neuronal migration.

Authors:  Ning Xu; Balasubramanian Bhagavath; Hyung-Goo Kim; Lisa Halvorson; Robert S Podolsky; Lynn P Chorich; Puttur Prasad; Wen-Cheng Xiong; Richard S Cameron; Lawrence C Layman
Journal:  Mol Cell Endocrinol       Date:  2009-12-16       Impact factor: 4.102

Review 4.  New understandings of the genetic basis of isolated idiopathic central hypogonadism.

Authors:  Marco Bonomi; Domenico Vladimiro Libri; Fabiana Guizzardi; Elena Guarducci; Elisabetta Maiolo; Elisa Pignatti; Roberta Asci; Luca Persani
Journal:  Asian J Androl       Date:  2011-12-05       Impact factor: 3.285

5.  Differential expression of nasal embryonic LHRH factor (NELF) variants in immortalized GnRH neuronal cell lines.

Authors:  Samuel D Quaynor; Lindsey Y Goldberg; Eun Kyung Ko; Robert K Stanley; Durkadin Demir; Hyung-Goo Kim; Lynn P Chorich; Richard S Cameron; Lawrence C Layman
Journal:  Mol Cell Endocrinol       Date:  2013-12-04       Impact factor: 4.102

6.  NELF knockout is associated with impaired pubertal development and subfertility.

Authors:  Samuel D Quaynor; Eun Kyung Ko; Lynn P Chorich; Megan E Sullivan; Durkadin Demir; Jennifer L Waller; Hyung-Goo Kim; Richard S Cameron; Lawrence C Layman
Journal:  Mol Cell Endocrinol       Date:  2015-02-27       Impact factor: 4.102

7.  Dysregulation of Semaphorin7A/β1-integrin signaling leads to defective GnRH-1 cell migration, abnormal gonadal development and altered fertility.

Authors:  Andrea Messina; Nicoletta Ferraris; Susan Wray; Gabriella Cagnoni; Duncan E Donohue; Filippo Casoni; Phillip R Kramer; Alwin A Derijck; Youri Adolfs; Aldo Fasolo; Ronald J Pasterkamp; Paolo Giacobini
Journal:  Hum Mol Genet       Date:  2011-09-08       Impact factor: 6.150

8.  Characterizing the novel protein p33MONOX.

Authors:  Manisha Mishra; Noriko Inoue; Klaus Heese
Journal:  Mol Cell Biochem       Date:  2010-12-14       Impact factor: 3.396

9.  Molecular analysis of KAL-1 in a series of Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism patients from Northwestern China.

Authors:  Kai-Fa Tang; Qi-Fei Wu; Tie-Jun Zou; Wei Xue; Xin-Yang Wang; Jun-Ping Xing
Journal:  Asian J Androl       Date:  2009-09-07       Impact factor: 3.285

Review 10.  GnRH, anosmia and hypogonadotropic hypogonadism--where are we?

Authors:  Paolo E Forni; Susan Wray
Journal:  Front Neuroendocrinol       Date:  2014-10-13       Impact factor: 8.606
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