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Literature DB >> 15017376

Azithromycin treatment failures in syphilis infections--San Francisco, California, 2002-2003.

Abstract

The San Francisco Department of Public Health (SFDPH) is investigating several clinical failures in syphilis patients treated with the macrolide antibiotic azithromycin. This report describes the use of azithromycin for syphilis treatment, recent treatment failures in San Francisco, and CDC recommendations for syphilis treatment. Clinicians should exercise caution in using azithromycin for treating incubating syphilis or syphilis infection until the risk and mechanism of failure are better understood.

Entities: Chemical Disease Species

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Year: 2004 PMID： 15017376

Source DB: PubMed Journal: MMWR Morb Mortal Wkly Rep ISSN： 0149-2195 Impact factor: 17.586

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Cited

11 in total

1. Azithromycin treatment failure among primary and secondary syphilis patients in Shanghai.

Authors: Pingyu Zhou; Kang Li; Haikong Lu; Yihong Qian; Xin Gu; Weiming Gong; Joseph D Tucker; Myron S Cohen
Journal: Sex Transm Dis Date: 2010-11 Impact factor: 2.830

2. [Syphilis treatment. German and international guidelines--a comparison].

Authors: H Schöfer
Journal: Hautarzt Date: 2005-02 Impact factor: 0.751

3. [Syphilis and HIV infection. Characteristic features of diagnosis, clinical assessment, and treatment].

Authors: A Potthoff; N H Brockmeyer
Journal: Hautarzt Date: 2005-02 Impact factor: 0.751

Review 4. The endemic treponematoses.

Authors: Lorenzo Giacani; Sheila A Lukehart
Journal: Clin Microbiol Rev Date: 2014-01 Impact factor: 26.132

5. The molecular epidemiology of Treponema pallidum subspecies pallidum.

Authors: Daphne Y Ma; Lorenzo Giacani; Arturo Centurión-Lara
Journal: Sex Health Date: 2015-04 Impact factor: 2.706

6. British Columbia's Experience after Implementation of the Treponema pallidum Reverse Algorithm and PCR Detection, 2015 to 2020.

Authors: Muhammad Morshed; Min-Kuang Lee; Jonathan Laley; Darrel Cook; Annie Mak; Navdeep Chahil; Venessa Ryan; Carolyn Montgomery; Sylvia Makaroff; Sarah Malleson; Barbra Arnold; Troy Grennan; Jason Wong; Mel Krajden
Journal: Microbiol Spectr Date: 2022-06-06

Azithromycin treatment failures in syphilis infections--San Francisco, California, 2002-2003.

1. Azithromycin treatment failure among primary and secondary syphilis patients in Shanghai.

2. [Syphilis treatment. German and international guidelines--a comparison].

3. [Syphilis and HIV infection. Characteristic features of diagnosis, clinical assessment, and treatment].

Review 4. The endemic treponematoses.

5. The molecular epidemiology of Treponema pallidum subspecies pallidum.

6. British Columbia's Experience after Implementation of the Treponema pallidum Reverse Algorithm and PCR Detection, 2015 to 2020.

Review 7. Global challenge of antibiotic-resistant Treponema pallidum.

8. Treatment of neurosyphilis.

Review 9. Syphilis in the HIV-infected patient: an update on epidemiology, diagnosis, and management.

10. Phylogenetic analysis of pbp genes in treponemes.