OBJECTIVE: To study alcohol consumption in relation to ovarian cancer risk in a prospective cohort study. METHODS: The Netherlands Cohort Study on diet and cancer was initiated in 1986. A self-administered questionnaire on dietary habits and other risk factors for cancer was completed by 62,573 postmenopausal women. Follow-up for cancer was established by annual record linkages with the Netherlands Cancer Registry. After 9.3 years of follow-up, 214 incident invasive epithelial ovarian cancer cases and 2211 subcohort members with complete data on alcohol intake were available for analysis. All incidence rate ratios (RRs) were corrected for age, use of oral contraceptives, parity, height, body mass index, energy intake and current cigarette smoking. RESULTS: The RRs of ovarian cancer for women who consumed up to 5, 15 and >15 g of alcohol per day were 1.13 (95% confidence interval, 95% CI = 0.79-1.63), 0.85 (95% CI = 0.53-1.37) and 0.92 (95% CI = 0.55-1.54), respectively, compared to non-drinkers. Alcohol consumption in the form of wine, beer or liquor was not associated with ovarian cancer risk. CONCLUSION: These data do not suggest a major association between alcohol intake and ovarian cancer risk in this population.
OBJECTIVE: To study alcohol consumption in relation to ovarian cancer risk in a prospective cohort study. METHODS: The Netherlands Cohort Study on diet and cancer was initiated in 1986. A self-administered questionnaire on dietary habits and other risk factors for cancer was completed by 62,573 postmenopausal women. Follow-up for cancer was established by annual record linkages with the Netherlands Cancer Registry. After 9.3 years of follow-up, 214 incident invasive epithelial ovarian cancer cases and 2211 subcohort members with complete data on alcohol intake were available for analysis. All incidence rate ratios (RRs) were corrected for age, use of oral contraceptives, parity, height, body mass index, energy intake and current cigarette smoking. RESULTS: The RRs of ovarian cancer for women who consumed up to 5, 15 and >15 g of alcohol per day were 1.13 (95% confidence interval, 95% CI = 0.79-1.63), 0.85 (95% CI = 0.53-1.37) and 0.92 (95% CI = 0.55-1.54), respectively, compared to non-drinkers. Alcohol consumption in the form of wine, beer or liquor was not associated with ovarian cancer risk. CONCLUSION: These data do not suggest a major association between alcohol intake and ovarian cancer risk in this population.
Authors: Margaret A Gates; Allison F Vitonis; Shelley S Tworoger; Bernard Rosner; Linda Titus-Ernstoff; Susan E Hankinson; Daniel W Cramer Journal: Int J Cancer Date: 2009-04-15 Impact factor: 7.396
Authors: Ellen T Chang; Alison J Canchola; Valerie S Lee; Christina A Clarke; David M Purdie; Peggy Reynolds; Leslie Bernstein; Daniel O Stram; Hoda Anton-Culver; Dennis Deapen; Harvey Mohrenweiser; David Peel; Rich Pinder; Ronald K Ross; Dee W West; William Wright; Argyrios Ziogas; Pamela L Horn-Ross Journal: Cancer Causes Control Date: 2007-02 Impact factor: 2.506
Authors: Linda E Kelemen; Elisa V Bandera; Kathryn L Terry; Mary Anne Rossing; Louise A Brinton; Jennifer A Doherty; Roberta B Ness; Susanne Krüger Kjaer; Jenny Chang-Claude; Martin Köbel; Galina Lurie; Pamela J Thompson; Michael E Carney; Kirsten Moysich; Robert Edwards; Clare Bunker; Allan Jensen; Estrid Høgdall; Daniel W Cramer; Allison F Vitonis; Sara H Olson; Melony King; Urmila Chandran; Jolanta Lissowska; Montserrat Garcia-Closas; Hannah Yang; Penelope M Webb; Joellen M Schildkraut; Marc T Goodman; Harvey A Risch Journal: BMC Cancer Date: 2013-01-22 Impact factor: 4.430
Authors: J M Genkinger; D J Hunter; D Spiegelman; K E Anderson; J E Buring; J L Freudenheim; R A Goldbohm; L Harnack; S E Hankinson; S C Larsson; M Leitzmann; M L McCullough; J Marshall; A B Miller; C Rodriguez; T E Rohan; A Schatzkin; L J Schouten; A Wolk; S M Zhang; S A Smith-Warner Journal: Br J Cancer Date: 2006-03-13 Impact factor: 7.640