| Literature DB >> 15012978 |
Roger Léger1, Corinne Benquet, Xicai Huang, Omar Quraishi, Pieter van Wyk, Dominique Bridon.
Abstract
Three peptide fragments of the kringle 5 region of plasminogen and their respective N- and C-terminus maleimido derivatives conjugated to Cys34 of human serum albumin were evaluated in vitro using a human umbilical vein endothelial cell (HUVEC) migration assay and a human plasma stability assay. The N-terminus maleimido derivative of the 64 to 74 segment of kringle 5 conjugated to human serum albumin possessed remarkable anti-migratory activity.Entities:
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Year: 2004 PMID： 15012978 DOI： 10.1016/j.bmcl.2003.12.025
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823