Literature DB >> 150116

Giant cell tumor of bone. Fine structural localization of alkaline phosphatase.

T Aparisi, B Arborgh, J L Ericsson.   

Abstract

The fine structural localization of nonspecific alkaline phosphatase was elucidated in two giant cell tumors of bone using lead as capturing ion and beta-glycerophosphate as substrate in the incubation solution. Lead phosphate precipitate--indicating presence of alkaline phosphatase--was demonstrated on the plasma membranes, and the membranes bordering vesicles and vacuoles of presumed endocytotic nature, in giant cells and type 1 stromal cells (fibroblast-like cells). The findings support the view that stromal cells type I and giant cells are histogenetically related.

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Year:  1978        PMID： 150116     DOI： 10.1007/bf00465595

Source DB:  PubMed          Journal:  Virchows Arch A Pathol Anat Histol        ISSN： 0340-1227


  16 in total

1.  [Cytologic study of giant cell tumors. Electron microscopy. Cyto-enzymology].

Authors:  J P Thiery; A Mazabraud; M C Voisin; G Lacroix; E Baviera
Journal:  Rev Chir Orthop Reparatrice Appar Mot       Date:  1975 Jul-Aug

2.  The histochemistry of giant-cell tumours (osteoclastoma and giant-cell epulis).

Authors:  W J PEPLER
Journal:  J Pathol Bacteriol       Date:  1958-10

3.  Giant cell tumor of bone: fine structural localization of acid phosphatase.

Authors:  T Aparisi; B Arborgh; J L Ericsson
Journal:  Virchows Arch A Pathol Anat Histol       Date:  1977-12-08

4.  Giant cell tumor of bone: detailed fine structural analysis of different cell components.

Authors:  T Aparisi; B Arborgh; J L Ericsson
Journal:  Virchows Arch A Pathol Anat Histol       Date:  1977-12-08

5.  Histochemical characteristics of giant cell bone tumours.

Authors:  N A Kraievski; N T Raikhlin; J N Soloviov
Journal:  Folia Histochem Cytochem (Krakow)       Date:  1970

6.  Fine structural localization of alkaline phosphatase in the fracture callus of the rat.

Authors:  G Göthlin; J L Ericsson
Journal:  Histochemie       Date:  1973

7.  On the mechanism of lysosomal enzyme secretion. Electron microscopic and histochemical studies on the epithelial cells of the rat's ventral prostate lobe.

Authors:  H J Helminen; J L Ericsson
Journal:  J Ultrastruct Res       Date:  1970-12

8.  The osteoclast: review of ultrastructure, origin, and structure-function relationship.

Authors:  G Göthlin; J L Ericsson
Journal:  Clin Orthop Relat Res       Date:  1976-10       Impact factor: 4.176

9.  Alkaline phosphatase activity in human polymorphonuclear leukocytes.

Authors:  M Borgers; F Thoné; J de Crée; W de Cock
Journal:  Histochem J       Date:  1978-01

10.  Contribution to the knowledge of the fine structure of chondrosarcoma of bone. With a note on the localization of alkaline phosphatase and "ATPase".

Authors:  T Aparisi; B Arborgh; J L Ericsson; G Göthlin; U Nilsonne
Journal:  Acta Pathol Microbiol Scand A       Date:  1978-03
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  3 in total

1.  In vitro bone resorption by isolated multinucleated giant cells from giant cell tumour of bone: light and electron microscopic study.

Authors:  J Kanehisa; T Izumo; M Takeuchi; T Yamanaka; T Fujii; H Takeuchi
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1991

2.  Giant cell tumor bone. Enzyme histochemical, biochemical and tissue culture studies.

Authors:  H Yoshida; M Akeho; T Yumoto
Journal:  Virchows Arch A Pathol Anat Histol       Date:  1982

3.  Human osteogenic sarcoma. Study of the ultrastructure, with special notes on the localization of alkaline and acid phosphatase.

Authors:  T Aparisi; A Stark; J L Ericsson
Journal:  Int Orthop       Date:  1982       Impact factor: 3.075
  3 in total

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