BACKGROUND: This investigation reports a 68-year-old man with a history of hepatocellular carcinoma (HCC) diagnosed 2 years previously who developed a single, easy-bleeding, pyogenic granuloma (PG)-like lesion on his right upper abdomen, located in the area of previous therapeutic percutaneous ethanol injection (PEI) for HCC treatment. The lesion developed 3 months after the injection. The tumor was found to be identical to his previous HCC. OBJECTIVE: To describe a case of cutaneous seeding of HCC during PEI presented as a PG-like lesion. To our knowledge, this is the first such case reported in the literature. METHODS: This is a case report and review the literature. RESULTS: Immunostainings for alpha-fetoprotein and hepatocyte monoclonal antibody confirmed the diagnosis. Besides, the patient had no other metastatic lesion. CONCLUSION: This tumor is believed to be caused by cutaneous seeding of HCC during PEI and is simulated clinically as a PG.
BACKGROUND: This investigation reports a 68-year-old man with a history of hepatocellular carcinoma (HCC) diagnosed 2 years previously who developed a single, easy-bleeding, pyogenic granuloma (PG)-like lesion on his right upper abdomen, located in the area of previous therapeutic percutaneous ethanol injection (PEI) for HCC treatment. The lesion developed 3 months after the injection. The tumor was found to be identical to his previous HCC. OBJECTIVE: To describe a case of cutaneous seeding of HCC during PEI presented as a PG-like lesion. To our knowledge, this is the first such case reported in the literature. METHODS: This is a case report and review the literature. RESULTS: Immunostainings for alpha-fetoprotein and hepatocyte monoclonal antibody confirmed the diagnosis. Besides, the patient had no other metastatic lesion. CONCLUSION: This tumor is believed to be caused by cutaneous seeding of HCC during PEI and is simulated clinically as a PG.
Authors: Dorothée Nashan; Marcel Lucas Müller; Markus Braun-Falco; Sebastian Reichenberger; Rolf-Markus Szeimies; Leena Bruckner-Tuderman Journal: J Cancer Res Clin Oncol Date: 2008-06-17 Impact factor: 4.553
Authors: L Zachau; C Zeckey; J Schlue; J Sander; C Meyer-Heithuis; M Winkler; J Klempnauer; H Schrem Journal: World J Surg Oncol Date: 2012-05-30 Impact factor: 2.754