Two cases of ventricular tachycardia with congenital left ventricular malformation in an adult.

Two patients without any risk factors for coronary artery disease presented with symptomatic, recurrent, nonsustained ventricular tachycardia. They were found to have a postero-lateral left ventricular aneurysm and diverticulum. Coronary angiography revealed normal coronary arteries. The 12-lead electrocardiogram showed sinus rhythm with frequent premature ventricular contractions. Their nonsustained ventricular tachycardias were reproduced by programmed electrical stimulation and was unresponsive to procainamide, mexiletine, and disopyramide. Aneurysmal resection and cryoablative surgery were performed. The pathological examination of the aneurysmal wall revealed focal defect of muscle fibers in case 1. On the other hand, the wall of case 2 was formed by all three cardiac layers. After surgery, ventricular programmed stimulation was negative, and premature ventricular contraction had disappeared.